FITC标记的T细胞2识别黑色素瘤抗原抗体_详细资料

产品信息

货号： LM-15474R-FITC 保存条件： -20 °C 浓度： 1mg/ml 应用范围： ICC=1:50-200 IF=1:50-200 形态：粉末、液体、冻干粉亚型： IGg 免疫原：详见说明书适应物种： Human, Mouse, Rat, 宿主： Human, Mouse, Rat, 标记物： FITC标记抗体名： Anti-HHAT/FITC 抗体英文名： Anti-HHAT/FITC 保质期： 1年抗原来源： Rabbit 克隆性：多克隆目录编号： LM-15474R-FITC 级别： 1 靶点：详见说明书数量：大量供应商：上海联迈生物工程有限公司规格： 100ul

FITC标记的T细胞2识别黑色素瘤抗原抗体

英文名称 Anti-HHAT/FITC

中文名称 FITC标记的T细胞2识别黑色素瘤抗原抗体

别    名 2810432O22Rik; AC115917.1; AI462858; FLJ10724; FLJ34867; Hedgehog acyltransferase; Hhat; HHAT_HUMAN; MART 2; MART-2; MART2; Melanoma antigen recognized by T cells 2; Melanoma antigen recognized by T-cells 2; MGC11697; OTTMUSP00000033669; Protein cysteine N palmitoyltransferase HHAT; Protein-cysteine N-palmitoyltransferase HHAT; RGD1311746; SKI1; Skinny hedgehog protein 1; Skinny hedgehog protein; Skn.

规格价格 100ul/2980元购买        大包装/询价

说明书 100ul

研究领域信号转导

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human, Mouse, Rat,

产品应用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 57kDa

性    状 Lyophilized or Liquid

浓    度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human HHAT

亚    型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品介绍 background:
HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1.

Function:
Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity).

Tissue Specificity:
Ubiquitously expressed in normal tissues and cancer cell lines.

Similarity:
Belongs to the membrane-bound acyltransferase family. HHAT subfamily.

Database links:
Entrez Gene: 57467 Human

Entrez Gene: 74770 Mouse

Entrez Gene: 301073 Rat

Omim: 608116 Human

SwissProt: Q9HCP6 Human

SwissProt: Q9D1G3 Mouse

Unigene: 476041 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

您可能感兴趣的产品

FITC标记的T细胞2识别黑色素瘤抗原抗体

产品信息

联系我们

关注我们

英文名称	Anti-HHAT/FITC
中文名称	FITC标记的T细胞2识别黑色素瘤抗原抗体
别名	2810432O22Rik; AC115917.1; AI462858; FLJ10724; FLJ34867; Hedgehog acyltransferase; Hhat; HHAT_HUMAN; MART 2; MART-2; MART2; Melanoma antigen recognized by T cells 2; Melanoma antigen recognized by T-cells 2; MGC11697; OTTMUSP00000033669; Protein cysteine N palmitoyltransferase HHAT; Protein-cysteine N-palmitoyltransferase HHAT; RGD1311746; SKI1; Skinny hedgehog protein 1; Skinny hedgehog protein; Skn.
规格价格	100ul/2980元购买大包装/询价
说明书	100ul
研究领域	信号转导
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human, Mouse, Rat,
产品应用	ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	57kDa
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human HHAT
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: HHAT is a 493 amino acid multi-pass membrane protein that localizes to the endoplasmic reticulum and belongs to the membrane-bound acyltransferase family. Expressed ubiquitously, HHAT functions to catalyze the N-terminal palmitoylation of SSH (slingshot homolog), an event that is required for SHH signaling pathways. HHAT is expressed in cancer cell lines, suggesting a role for HHAT in tumorigenesis. The gene encoding HHAT maps to human chromosome 1 and is expressed as four alternatively spliced isoforms. Chromosome 1 is the largest human chromosome, spanning about 260 million base pairs and making up 8% of the human genome. Several disorders, including Stickler syndrome, Parkinsons Disease, Gaucher disease, malignant melanoma and Usher syndrome, are caused by defects in genes that localize to chromosome 1. Function: Catalyzes N-terminal palmitoylation of SHH; which is required for SHH signaling (By similarity). May bind GTP. Subcellular Location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Tissue Specificity: Ubiquitously expressed in normal tissues and cancer cell lines. Similarity: Belongs to the membrane-bound acyltransferase family. HHAT subfamily. Database links: Entrez Gene: 57467 Human Entrez Gene: 74770 Mouse Entrez Gene: 301073 Rat Omim: 608116 Human SwissProt: Q9HCP6 Human SwissProt: Q9D1G3 Mouse Unigene: 476041 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.