Recombinant Clostridium botulinum Botulinum neurotoxin type D(botD),partial

host_species:E.coli

purification:Greater than 85% as determined by SDS-PAGE.

other_names:Bontoxilysin-D

accession_no:P19321

calculated_mw:64.5 kDa

tag info:N-terminal 6xHis-B2M-tagged

Immunogen Description:Expression Region:1-442aa
Sequence Info:Partial

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:Botulinum toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that cleaves the '60-Lys-|-Leu-61' bond of synaptobrevins-1 and -2.

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