

品Pai:miltenyi,产品名称:CD140a-PerCP-Vio700, mouse 200 tests
CD140a antibodies, mouse - Miltenyi Biotec
货号:130-109-740
Clone REA637 recognizes the mouse CD140a antigen, a single-pass type I membrane protein, also known as platelet-derived growth factor receptor alpha (PDGFRα). CD140a is a receptor tyrosine kinase that forms homodimers or heterodimers with CD140b (PDGFRβ). Receptor dimerization and transphosphorylation at tyrosine residues activates the intracellular kinase activity. CD140a is broadly expressed in embryonic tissue, mostly in cells of mesodermal origin in adult tissue, and embryonic stem cell–derived cardiomyogenic cells. Expression of CD140a is associated with various malignancies.
Additional information: Clone REA637 displays negligible binding to Fc receptors.
Alternative namesPDGF-R-alpha, PDGFR-alpha, PDGFR-α
Clone and isotype
Clone | Isotype |
---|
REA637 | recombinant human IgG1 |

温馨提示:不可用于临床ZL。