CD321 (JAM1) antibodies, human

品Pai:miltenyi，产品名称：CD321 (JAM-1)-Biotin, human 30 tests
CD321 (JAM1) antibodies, human - Miltenyi Biotec
货号：130-109-479
Clone REA605 recognizes the human CD321 antigen, a cell-surface adhesion molecule, also known as JAM1 or JAMA. CD321 is a type I transmembrane glycoprotein belonging to the immunoglobin superfamily. It has two extracellular Ig-like domains, a transmembrane region and a short cytosolic tail.
CD321 is expressed on a variety of cell types: erythrocytes, leukocytes, platelets, as well as endothelial and epithelial cells. CD321 has different functions. It is a regulator of tight junction assembly in epithelia and acts as a receptor for reovirus. Furthermore CD321 binds integrin LFA1 and is involved in leukocyte transmigration. In addition, CD321 is a platelet receptor.
Additional information: Clone REA605 displays negligible binding to Fc receptors.

Alternative namesJAM-1, JAM-A, PAM-1, F11 R

Clone and isotype

Clone	Isotype
REA605	recombinant human IgG1