品Pai:miltenyi,产品名称:Anti-TIM-3-VioBright FITC, m 200 tests
Anti-TIM-3 antibodies, mouse - Miltenyi Biotec
货号:130-109-449
Clone REA602 reacts with the mouse TIM-3 antigen, which is a Tʜ1-specific cell surface protein expressed by differentiated CD4+ Tʜ1 and CD8+ Tc1 cells and macrophages. It is absent on CD4+ Tʜ2 and CD8+ Tc2 cells. TIM-3 has been proposed to inhibit Tʜ1-mediated immune responses. TIM-3 absence enhances the severity of experimental autoimmune encephalomyelitis in mice. The interaction of TIM-3 and Galectin-9 induces apoptosis of Tʜ1 cells.
Additional information: Clone REA602 displays negligible binding to Fc receptors.
Alternative namesTim3
Clone and isotype
Clone | Isotype |
---|
REA602 | recombinant human IgG1 |
温馨提示:不可用于临床ZL。