HLA-A2-PerCP-Vio700/Anti-HLA-A2 antibodies, human

品Pai:miltenyi，产品名称：Anti-HLA-A2-PerCP-Vio700, human
Anti-HLA-A2 antibodies, human - Miltenyi Biotec
货号：130-107-933
Clone REA517 recognizes the class I human leukocyte antigen A2 (HLA-A2). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and a soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of three domains, one of which comprises the peptide binding groove. Antigens binding to class I molecules are 8–10 amino acids long and play an important role in recognition of virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells.
Additional information: Clone REA517 displays negligible binding to Fc receptors.

Alternative namesMHC class I HLA-A2

Clone and isotype

Clone	Isotype
REA517	recombinant human IgG1