品Pai:miltenyi,产品名称:CD49f-VioBright FITC, human, mouse
CD49f antibodies, human and mouse - Miltenyi Biotec
货号:130-107-780
Clone REA518 recognizes the human and mouse CD49f antigen, a 120 kD single-pass type I membrane protein, which is also known as integrin alpha-6 (ITGA6). Integrins are integral cell-surface proteins composed of an α chain and a β chain and are involved in cell adhesion as well as cell-surface mediated signaling. CD49f associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, which plays a critical structural role in the hemidesmosome and constitutes a receptor for laminin in epithelial cells. CD49f is furthermore expressed on T cells, monocytes, platelets, endothelial cells, trophoblasts of placenta, and spermatogonial stem cells.
Additional information: Clone REA518 displays negligible binding to Fc receptors.
Alternative namesITGA6, CD49fB, VLA-6, ITGA6, VLA-6α
Clone and isotype
Clone | Isotype |
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REA518 | recombinant human IgG1 |
温馨提示:不可用于临床ZL。