CD304 (BDCA-4)-VioBright FITC/CD304 (BDCA-4) antibodies, human

品Pai:miltenyi，产品名称：CD304 (BDCA-4)-VioBright FITC, Human
CD304 (BDCA-4) antibodies, human - Miltenyi Biotec
货号：130-104-272
Clone AD5-17F6 recognizes the human CD304 (BDCA-4) antigen. Like CD303 (BDCA-2), the CD304 (BDCA-4) antigen¹ is specifically expressed on human plasmacytoid dendritic cells in blood^1–3 and bone marrow⁴. Unlike CD303 (BDCA-2), expression of CD304 (BDCA-4) is up-regulated on plasmacytoid dendritic cells and induced on myeloid cells upon culturing.⁴ In inflamed tonsils, CD304 (BDCA-4) expression, apart from plasmacytoid dendritic cells, is also detected primarily on follicular B helper memory T cells.⁴ CD304 (BDCA-4) is identical to neuropilin-1 (NP-1),⁴ a neuronal receptor, which is known to be expressed on numerous nonhematopoietic cell types, including neurons, endothelial, and tumor cells. CD1a⁺ dendritic cells generated ex vivo from monocytes or hematopoietic precursor cells are CD304 (BDCA-4)⁺ but CD303 (BDCA-2)^–.¹

Alternative namesNRP1, BDCA-4, NP1, Nrp, VEGF165R

Clone and isotype

Clone	Isotype
AD5-17F6	mouse IgG1