KLRG1 (MAFA)-FITC/Anti-KLRG1 antibodies, human

品Pai:miltenyi，产品名称：Anti-KLRG1 (MAFA)-FITC, human
Anti-KLRG1 antibodies, human - Miltenyi Biotec
货号：130-103-640
Clone REA261 recognizes the killer cell lectin-like receptor subfamily G member 1 (KLRG1) antigen, a transmembrane protein, which is also known as C-type lectin domain family 15 member A (CLEC1) or ITIM-containing receptor MAFA-L. KLRG1 is expressed by basophils, CD4 and CD8 T cells that exhibit a memory cell phenotype, and by a large proportion of peripheral blood NK cells. Expression of KLRG1 by virus-specific CD8⁺ T cells is induced by repetitive antigen stimulation and it differs in chronic versus resolved viral infections. T cells expressing KLRG1 exhibit a poor proliferation potential, while their ability to secrete gamma interferon is preserved. Thus, KLRG1 is a convenient marker for early T cell–differentiation.
Additional information: Clone REA261 displays negligible binding to Fc receptors.

Alternative namesKiller cell lectin-like receptor subfamily G member 1, CLEC1, MAFA, MAFA-2F1, MAFA-L, 2F1

Clone and isotype

Clone	Isotype
REA261	recombinant human IgG1