Anti-Dectin-2 antibodies, mouse

品Pai:miltenyi，产品名称：Anti-Dectin-2-Fitc, mouse 60 tests
Anti-Dectin-2 antibodies, mouse - Miltenyi Biotec
货号：130-103-011
Clone KVa7-6E7 specifically recognizes mouse dendritic cell–associated C-type lectin 2 (Dectin-2). Dectin-2 is a type II membrane protein and contains a single carbohydrate recognition domain. Like other C-type lectins, mouse Dectin-2 has conserved motifs for the Ca²⁺-dependent recognition of mannose. Dectin-2 is located in the natural killer gene complex of chromosome 6. Genomic analyses show that beside a full length Dectin-2 transcript two truncated isoforms are produced by alternative splicing, encoding transmembrane proteins of 168–209 amino acids.¹^,² The expression of Dectin-2 on mouse monocytes and macrophages can be induced by zymosan and thioglycollate.³ Dectin-2 plays a physiological role in antigen presentation and antigen targeting via Dectin-2 can induce a CD8⁺ T cell response.⁴

Alternative namesCLEC4N, Clec6a, Clecsf10, Nkcl

Clone and isotype

Clone	Isotype
KVa7-6E7	rat IgG2a