CD196 (CCR6)-PE-Vio770/CD196 (CCR6) antibodies, human

品Pai:miltenyi，产品名称：CD196 (CCR6)-PE-Vio770, human
CD196 (CCR6) antibodies, human - Miltenyi Biotec
货号：130-100-381
Clone REA190 recognizes CD196 (CCR6), a seven transmembrane G protein–coupled receptor, which belongs to the family of beta chemokine receptors. Expression of CD196 is found on T cells, naive and memory B cells, and immature dendritic cells. CD196 selectivly binds chemokine MIP-3α/CCL20, which is secreted by a number of cells and tissues. In addition, members of a family of small cationic antimicrobial peptides, such as human β-defensins (hBD)-1 and -2, which are released by epithelial cells in response to microbial invasion or proinflammatory stimuli, are also shown to bind to CCR6. This interaction induce chemotaxis in immature dendritic cells and memory T cells.
Additional information: Clone REA190 displays negligible binding to Fc receptors.

Alternative namesCCR6, BN-1, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22

Clone and isotype

Clone	Isotype
REA190	recombinant human IgG1