KI-67-PerCP-Vio700/Anti-Ki-67 antibodies, human and mouse

品Pai:miltenyi，产品名称：Anti-KI-67-PerCP-Vio700, human&mouse
Anti-Ki-67 antibodies, human and mouse - Miltenyi Biotec
货号：130-100-292
Clone REA183 recognizes Ki-67 antigen, a nuclear and nucleolar protein, which is strictly associated with cell proliferation. Two Ki-67 isoforms with molecular weight, 395 and 345 kDa are known. Both isoforms contain 16 “Ki-67 repeat“ sequences, each of which includes a conserved 66 bp “Ki-67 motif“. Expression of Ki-67 protein is present during all active phases of the cell cycle (G(1), S, G(2), and mitosis), but is absent from resting cells (G(0)). Due to strict association of Ki-67 with proliferating cells, Ki-67 is often used as an indicator of the “growth fraction“ of a given cell population. The N-terminal portion of Ki-67 contains a forkhead associated (FHA)1 domain, which is involved in interaction with proteins such as Hklp2 and NIFK.
Additional information: Clone REA183 displays negligible binding to Fc receptors.

Alternative namesMKI67, KIA, MIB-, MIB-1, PPP1R105, Ki67

Clone and isotype

Clone	Isotype
REA183	recombinant human IgG1