品Pai:miltenyi,产品名称:CD206-PE-Vio770, human
CD206 antibodies, human - Miltenyi Biotec
货号:130-100-152
The mannose receptor (MR), also known as macrophage MR or CD206, is a 162–175 kDa type I membrane protein. It contains an N-terminal cystein-rich domain and eight C-type lectin-like domains (CTLDs), beside a transmembrane and a cytoplasmic domain. CD206 is expressed by macrophages, dendritic cells, and subsets of endothelial cells, but not on monocytes. The MR recognizes multiple mainly microbial carbohydrates with mannose, fucose, or N-acetyl glucosamine residues. The MR mediates endocytosis and phagocytosis, linked to antigen presentation. It plays an important role in host defense and provides a link between innate and adaptive immunity.
Alternative namesMRC1, CLEC13D, CLEC13DL, MMR, MRC1L1
Clone and isotype
Clone | Isotype |
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DCN228 | mouse IgG1κ |
温馨提示:不可用于临床ZL。