CD172a (SIRPa)-FITC/CD172a (SIRPα) antibodies, human

品Pai:miltenyi，产品名称：CD172a (SIRPa)-FITC, human
CD172a (SIRPα) antibodies, human - Miltenyi Biotec
货号：130-099-896
Clone REA144 recognizes CD172a, which is also known as signal regulatory protein (SIRP)α. CD172a belongs to the Ig superfamily and is 75-110 kDa, single-pass, type I regulatory membrane protein. Expression of CD172a is found primarily on hematopoietic stem cells, neurons and myeloid cells such as macrophages, monocytes, dendritic cells, granulocytes and myeloid progenitors. CD172a phosphorylated at intracellular tyrosine sites, in response to extracellular stimuli, serves as the docking site for phosphatases such as SHP-1, SHP-2, or SHIP, which inturn desphosphorylate molecules involved in regulating various physiological effects. CD47 has been suggested as a ligand of CD172a. Additional Information: Clone REA144 displays negligible binding to Fc receptors.

Alternative namesSIRPα, Bit, Mfr, MYD-1, P84, Ptpns1, SHPS-1, Sirp, SIRPα

Clone and isotype

Clone	Isotype
REA144	recombinant human IgG1