货号： 130-099-523 CAS号： 130-099-523 供应商： 科敏商城 数量： 大量 英文名： HLA-A2/Anti-HLA-A2 A28 antibodies, human 保质期： 见说明书 保存条件： 见说明书
品Pai:miltenyi，产品名称：Anti-HLA-A2, 28-PE-Vio770, human
Anti-HLA-A2 A28 antibodies, human - Miltenyi Biotec
货号：130-099-523
Clone REA142 recognizes HLA A2 and HLA A28, class I human leukocyte antigens (HLA). Expressed on the surface of most nucleated cells, class I molecules are heterodimeric molecules and consist of a type I integral membrane α heavy chain and soluble β2 microglobulin protein. The extracellular region of the heavy chain further consists of 3 domains, one of which comprises the peptide binding groove. Antigens binding to class I molecules are 8-10 amino acids long and play an important role in recognition of the virus infected and malignant cells by cytotoxic T lymphocytes (CTLs). In addition, class I molecules interact with NK cell receptors to modulate the activity of NK cells. Additional Information: Clone REA142 displays negligible binding to Fc receptors.
| Clone | Isotype |
|---|---|
| REA142 | recombinant human IgG1 |
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