Senescence β-Galactosidase Staining Kit

品Pai:CST，产品名称：Senescence β-Galactosidase Staining Kit #9860
英文名称：Senescence β-Galactosidase Staining Kit
Product name：Senescence β-Galactosidase Staining Kit #9860
Isotype：Mouse IgG2a
Sensitivity：Endogenous
Background： Limited capacity to replicate is a defining characteristic of most normal cells and culminates in senescence, an arrested state in which the cell remains viable (1). Senescent cells are not stimulated to divide by serum or passage in culture, and senescence invokes a specific cell cycle profile that differs from most damage-induced arrest processes or contact inhibition (2). An enlarged cell size, expression of pH-dependent beta-galactosidase activity (3), and an altered pattern of gene expression (4,5) further characterize senescent cells.

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Product Description:

The Senescence β-Galactosidase Staining Kit is designed to conveniently provide reagents needed to detect β-galactosidase activity at pH 6, a known characteristic of senescent cells not found in presenescent, quiescent or immortal cells (3). Papers have published using this kit in both cells and frozen tissue. The kit includes all reagents necessary for this assay.