FITC标记的睾丸特异性碱性蛋白Y2抗体_详细资料

产品信息

货号： LM-12882R-FITC 保存条件： -20 °C 浓度： 1mg/ml 应用范围： ICC=1:50-200 IF=1:50-200 形态：粉末、液体、冻干粉亚型： IGg 免疫原：详见说明书适应物种： Human, 宿主： Human, 标记物： FITC标记抗体名： Anti-BPY2/FITC 抗体英文名： Anti-BPY2/FITC 保质期： 1年抗原来源： Rabbit 克隆性：多克隆目录编号： LM-12882R-FITC 级别： 1 靶点：详见说明书数量：大量供应商：上海联迈生物工程有限公司规格： 100ul

FITC标记的睾丸特异性碱性蛋白Y2抗体

英文名称 Anti-BPY2/FITC

中文名称 FITC标记的睾丸特异性碱性蛋白Y2抗体

别    名 Basic charge; Basic charge Y linked 2; Basic charge Y linked 2C; Basic protein on Y chromosome 2; BPY2A; BPY2B; BPY2C; Testis specific basic protein on Y 2; Testis specific basic protein Y 2; Testis-specific basic protein Y 2; Variable charge Y linked 2; Variably charged protein Y 2; VCY2; VCY2_HUMAN; VCY2A; VCY2B; VCY2C; Y-linked 2.

规格价格 100ul/2980元购买        大包装/询价

说明书 100ul

研究领域细胞生物  发育生物学  干细胞

抗体来源 Rabbit

克隆类型 Polyclonal

交叉反应 Human,

产品应用 ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.

分子量 12kDa

性    状 Lyophilized or Liquid

浓    度 1mg/ml

免疫原 KLH conjugated synthetic peptide derived from human BPY2

亚    型 IgG

纯化方法 affinity purified by Protein A

储存液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.

产品介绍 background:
Mammalian spermatogenesis a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network.

Subunit:
Interacts with MAP1S. Interacts with UBE3A (via HECTdomain).

Tissue Specificity:
Expressed exclusively in testis. Expressed in ejaculated spermatozoa of germ cell. Expressed in the nuclei of spermatogonia, spermatocytes, and round spermatids, except elongated spermatids (at protein level).

Similarity:
Belongs to the VCX/VCY family.

Database links:
UniProtKB/Swiss-Prot: O14599.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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英文名称	Anti-BPY2/FITC
中文名称	FITC标记的睾丸特异性碱性蛋白Y2抗体
别名	Basic charge; Basic charge Y linked 2; Basic charge Y linked 2C; Basic protein on Y chromosome 2; BPY2A; BPY2B; BPY2C; Testis specific basic protein on Y 2; Testis specific basic protein Y 2; Testis-specific basic protein Y 2; Variable charge Y linked 2; Variably charged protein Y 2; VCY2; VCY2_HUMAN; VCY2A; VCY2B; VCY2C; Y-linked 2.
规格价格	100ul/2980元购买大包装/询价
说明书	100ul
研究领域	细胞生物发育生物学干细胞
抗体来源	Rabbit
克隆类型	Polyclonal
交叉反应	Human,
产品应用	ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分子量	12kDa
性状	Lyophilized or Liquid
浓度	1mg/ml
免疫原	KLH conjugated synthetic peptide derived from human BPY2
亚型	IgG
纯化方法	affinity purified by Protein A
储存液	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍	background: Mammalian spermatogenesis a complex developmental process. Mutations at multiple loci and in structurally and functionally disparate genes in the genome affect gametogenesis. The analysis of mutations has provided insight into biochemical pathways required for completion of this process. The basic protein on Y chromosome 2 gene (BPY2, also designated VCY2) is located in a frequently deleted azoospermia factor c region. Three copies (paralogs) of the BPY2 gene (BPY2A, BPY2B, BPY2C) reside in the AZFc region. BPY2 protein expression is localized to the nuclei of spermatogonia, spermatocytes and round spermatids, but is absent from elongated spermatids. Impaired expression of BPY2 in infertile men suggests its involvement in male germ cell development. BPY2 interacts with MAP-1S, which shares homology with microtubule-associated proteins (MAPs), suggesting a role for BPY2 within the cytoskeletal network. Subunit: Interacts with MAP1S. Interacts with UBE3A (via HECTdomain). Tissue Specificity: Expressed exclusively in testis. Expressed in ejaculated spermatozoa of germ cell. Expressed in the nuclei of spermatogonia, spermatocytes, and round spermatids, except elongated spermatids (at protein level). Similarity: Belongs to the VCX/VCY family. Database links: UniProtKB/Swiss-Prot: O14599.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.