anti-p40 / DeltaNp63 antibody [SQab1740]

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. [provided by RefSeq, Jul 2008]

上海帛龙生物科技有限公司Shanghai Bio-Platform Technology Company是一家由生物行业从业多年的销售精英和科技精英联合创办的创新型高科技企业，自公司成立以来一直以“客户至上”为公司核心价值观，积极提升专业化水平，打造高水平的顾问式销售服务团队，专注于为生命科学和生物技术领域的客户提供高质量的产品、高品质的服务、快速的物流渠道。我们将努力将“帛龙生物”打造华东地区生命科学一站式采购服务平台，成为客户值得信赖的综合贸易产品供应商！

公司业务涵盖以下几个方向：
1） 抗体业务：abcam，arigo，Miltenyi Biotec，PTM Bio等品Pai抗体业务！
2） 细胞培养类产品和服务！
3） 分子类产品：siRNA、shRNA、基因文库、分子探针等！
4） 实验设备及仪器：CytoSMART细胞成像仪、Muse全能细胞质控仪等！
5） 抗体定制服务：phospho、甲基化、乙酰化、丙酰化等多种类型蛋白修饰抗体！

官方代理合作品Pai包括：abcam，arigo，Miltenyi Biotec，GE Dharmacon，Lonza，Merck Muse。其他授权代理品Pai有：PromoCell，Biomiga，LGC Genomics，Crystal，Harvard apparatus，Cyanagen，PTM Bio等众多品Pai，为客户提供一站式优质服务！