Sarafotoxin S6d

Name:PAR-2 (1-6),Protease Activated Receptor-2 (1-6), (mouse, rat);
Sequence(Three Letter):H-Ser-Leu-Ile-Gly-Arg-Leu-OH (trifluoroacetate salt);
Sequence(One Letter):SLIGRL;
Cas:[164081-25-8];
Formula:C29H55N9O8;
M.W.:657.81;
Size:1mg,5mg,10mg,50mg,100mg,1g;
Purity:80%,90%,95%,98%,99%;
Storage Temp:Store at -20°C. Keep tightly closed. Store in a cool dry place.;
Reference:R.J.Santulli et al., Proc. Natl. Acad. Sci. USA, 92, 9151 (1995)A. Bhattacharya et al., J. Pharmacol. Exp. Ther., 297, 573 (2001)B. Al-Ani, et al., J. of Physiol. Pharmacol., 73, 1203 (1995);
Description:This peptide is the tethered ligand sequence of mouse PAR-2, which like the thrombin receptor is a protease-activated receptor present in keratinocytes. This peptide was found to be equipotent with SFLLRN in activating keratinocyte inositolphospholipid hydrolysis and calcium mobilization.