Neuron Specific Peptide

Name:Z-DEVD-AMC;
Sequence(Three Letter):Z-Asp-Glu-Val-Asp-AMC;
Sequence(One Letter):Z-DEVD-AMC;
Formula:C36H41N5O14;
M.W.:767.8;
Size:1mg,5mg,10mg,50mg,100mg,1g;
Purity:80%,90%,95%,98%,99%;
Storage Temp:Store at -20°C. Keep tightly closed. Store in a cool dry place.;
Reference:Koeplinger KA, et al. (2000) Protein Expr Purif 18, 378-87Garcia-Calvo M, et al. (1998) J Biol Chem 273, 32608-13Thornberry NA, et al. (1997) J Biol Chem 272, 17907-11Rano TA, et al. (1997) Chem Biol 4, 149-55Margolin N, et al. (1997) J Biol Chem 272, 7223-8Mizushima N, et al. (1996) FEBS Lett 395, 267-71Faubion WA, et al. (1999) J Clin Invest 103, 137-45.;
Description:AMC (7-amino-4-methylcoumarin) derived caspase substrates are widely used for the fluorimetric detection of various caspase activities. Cleavage of AMC peptides by caspases generates strongly fluorescent AMC that is monitored fluorimetrically at 440-460 nm with excitation of 340-350 nm. Caspase-3 and caspase-7 substrates