Histatin-8; Hemagglutination-Inhibiting Peptide (HIP)

Name:PrP,Prion Peptide (106-126), human;
Sequence(Three Letter):H-Lys-Thr-Asn-Met-Lys-His-Met-Ala-Gly-Ala-Ala-Ala-Ala-Gly-Ala-Val-Val-Gly-Gly-Leu-Gly-OH (trifluoroacetate salt);
Sequence(One Letter):KTNMKHMAGAAAAGAVVGGLG;
Cas:[148439-49-0];
Formula:C80H138N26O24S2;
M.W.:1912.3;
Size:1mg,5mg,10mg,50mg,100mg,1g;
Purity:80%,90%,95%,98%,99%;
Storage Temp:Store at -20°C. Keep tightly closed. Store in a cool dry place.;
Reference:Diomede, L. et al. Biochem. J. 320, 563 (1996) Florio, T. et al. J. Neurosci. Res. 54, 341 (1998).;
Description:This peptide increases membrane microviscosity, intracellular Ca2+ concentration and cell migration in circulating leucocytes, and oxygen production in monocytes and neutrophils. It also induces apoptotic cell death and impairment of L-type voltage-sensitive calcium channel activity in the GH3 cell lines. PrP (106126) stimulates leucocyte migration in a dose-dependent manner.