13C/15N标记抗肿瘤药/氘代同位素标记肿瘤YZ剂
13C/15N标记抗肿瘤药/氘代同位素标记肿瘤YZ剂
13C/15N标记抗肿瘤药/氘代同位素标记肿瘤YZ剂
美国剑桥同位素CIL是世界上个生产稳定性同位素标记化合物的生产商,以其领先的技术雄踞同位素分离领域。20年来,CIL一直研究稳定性同位素与稳定性同位素标记化合物的开发,生产。主要标记性同位素有13C、12C、D、15N、18O和17O,目前已经拥有8000多种标记化合物。CIL的产品均能应用于不同的领域,如物理,化学,生物医学,分析,诊断研究以及环境测试。
Cambridge Isotope Laboratories, Inc. (CIL) is the world’s leading producer of stable isotopes and stable isotope-labeled compounds. With over 400 employees and laboratories in four countries, CIL specializes in the process of labeling biochemical and organic compounds with highly enriched, stable (nonradioactive) isotopes of carbon, hydrogen, nitrogen and oxygen. Our chemists substitute common atoms (e.g., 1H, 12C, 14N, 16O) with rare, highly valued isotopes (e.g., 2H or D, 13C, 15N,18O) so that the final product can be readily measured or traced using mass spectrometry (MS) or nuclear magnetic resonance (NMR). CIL’s products are utilized in laboratories, medical, government and academic research centers and health care facilities worldwide. We are proud that CIL products have contributed to medical advancements in cancer research, new-drug development, environmental analysis, genomics and proteomics, and medical diagnostic research. In the past decade, as the fields of proteomics and metabolomics have developed as leading techniques for determining biomarkers for disease presence, progression and the monitoring of therapeutic response, CIL has worked closely with industry leaders and researchers to provide the stable isotope-labeled tools needed for improved quantitation of complex systems.CIL's vision began when it was founded in 1981 by Dr. Joel Bradley, an organic chemist from MIT. Drawing on a commitment to high-quality products, superior customer service, innovative new products and breadth of product lines, CIL quickly emerged as a leader in its field. CIL now produces more than 15,000 products and has ISO 13485, ISO/IEC 17025 and ISO Guide 34 quality systems, as well as cGMP production capabilities. Over the past several decades CIL has increased its global footprint and now has over 400 employees in its facilities located in four countries. The CIL group is comprised of five companies: Cambridge Isotope Laboratories, Inc. (CIL) and CIL Isotope Separations, LLC (CIS) in the US; CIL Canada in Montreal, Canada; Euriso-Top in Saclay, France; and ABX GmbH in Dresden, Germany. CIL’s state-of-the-art production facilities are located at the company’s headquarters in Tewksbury, Massachusetts, and the company’s primary production laboratories are located in Andover, Massachusetts. Our isotope-separation facility located in Xenia, Ohio, houses the world’s largest 13C and 18O isotope-separation facilities and the world’s only commercial D2O enrichment columns.产品分类:
1)定制合成化合物(Custom Synthesis):CIL一直为医药、农业、政府和环境各界成功地完成多种化合物的合成。对客户所要求的标记化合物, CIL都会对其进行研究和选择更合适的标记。
2)代谢底物( metabolic Substrates ):CIL提供Z完全的代谢分析底物,包括用于研究蛋白质和氨基酸代谢的氨基酸、葡萄糖代谢的碳水化合物和脂解作用的脂肪酸等。稳定性同位素标记物质使研究者能以安全的方式对活体内的代谢途径进行研究。
3)法医检验( Forensics ):对于复杂物质中低含量分析物的量化检测,Z精确的方法是同位素稀释和质谱两种技术结合。CIL为 法医检验提供量化的同位素标记ZL药物标准。
4)NMR 溶剂 ( NMR Solvents ):应用于结构分析、定量分析和纯度分析、化学途径与反应机、反应动力学等。
5)环境污染物标准液( Environmental Contaminant Standards ):CIL使一系列环境标准的概念得以发展,这些国际标准均由世界上先进的超痕量分析实验室检测和校正。 二十多年来,CIL生产的二氧(杂)芑、二垩英、呋喃和PCBs、PAHs符合国际"Gold Standards"。检测对象包括空气、 水、土壤、沉淀物和食品等。
6)13C的分离物 (13C Separation ):13C的年产量达120千克,使CIL成为世界上13C的生产商,也是诊断和研究应用领域13C的重要供应商。
7)18O的分离物 (18O Separation ):CIL生产的18O水, 既有符合PET技术要求的高丰度18O水(96%), 也有适合代谢研究实验的低丰度18O水(10%)。
8)同位素标记金属(Isotopic metal):CIL提供大量种类齐全的稳定同位素标记金属及金属化合物。Cambridge Isotope Laboratories, Inc. (CIL) is the world’s leading producer of stable isotopes and stable isotope-labeled compounds. Below you will find a list of categories in which CIL's stable isotope-labeled products can be found. Here you can view products by compound, access technical information, request a quote or a custom synthesis. You may also use the Advanced Search tool to help you with your search.剑桥同位素实验室(CIL)是世界上稳定同位素和稳定同位素标记化合物的主要生产商。在下面的列表中,您可以找到CIL代码的稳定同位素标记的产品。在这里,您可以通过化合物查看产品、访问技术信息、请求报价或自定义合成。你也可以使用高级搜索工具来帮助你搜索。dicyclomine D4 HClAlimemazine D6N-Desmethyl Sildenafil-Nizatidine-d3Venetoclax D8Deracoxib D3Tadalafil-d3Tamoxifen-D6N-Desmethyl Tamoxifen-DTamoxifen-d5N-Desmethyl tamoxifen-dRilmenidine-d4Sarpogrelate-D3 HClSarpogrelate MetaboliteAgomelatine-d3Tauro Obeticholic acidGlyco-obeticholic acid-Obeticholic Acid-d5Agomelatine-d6phenylmethanol-dphenylmethan-d2-olMETHYL-D3 P-TOLUENESULFCelecoxib-d7Tenofovir Alafenamide-dSacubitril-d4Colchicine-D6Venetoclax D8Chidamide D4Olaparib-D8Osimertinib d6Cariprazine D8Flibanserin-D8Brexpiprazole-d8Eluxadoline D3Safinamide-d4Oseltamivir-d3 CarboxylOseltamivir-d3Benzoic-d5 AcidRac Indapamide-d31-(Phenyl-D5)-EthanoneBromobenzene-d5Benzyl-d5 BromideBenzyl-D7 BromideBenzyl-d7 AlcoholChlorobenzene-D5Toluene-d8methylbenzene-d5(S)-Phenylglycine D5(R)-Phenylglycine D54-Ethoxycarbonylphenylb4-Carboxyphenylboronic4-Tolylboronic acid D7Phenylboronic acid D51,2-Phenylenediamine-3,Ethyl 4-chlorobenzoateEthyl 4-bromobenzoate D4-BROMOBENZOIC-D4 ACIDFebuxostat-D7IODOMETHANE-D3Oseltamivir D5 Hydrochloride头孢克肟-13C-15N2头孢泊肟-D3头孢泊肟-D3佐米曲普坦-D6佐米曲普坦-D6利鲁唑-13C-15N2利鲁唑-13C-15N2原儿茶醛-13C原儿茶醛-13C去乙基阿莫地喹-D3去乙基阿莫地喹-D3去乙基阿莫地喹-D5去乙基阿莫地喹-D5去甲基佐米曲普坦去甲基佐米曲普坦去甲基佐米曲普坦-D3去甲基佐米曲普坦-D3左旋布洛芬-D3左旋布洛芬-D3吉西他滨-13C吉西他滨-13C吉西他滨-13C-15N2吉西他滨-13C-15N2吉西他滨代谢物-13C吉西他滨代谢物-13C吉西他滨代谢物-13C-15N2吉西他滨代谢物-13C-15N2吉西他滨盐酸盐-13C吉西他滨盐酸盐-13C吉西他滨盐酸盐-13C-15N2吉西他滨盐酸盐-13C-15N2和厚朴酚-13C6
温馨提示:不可用于临床ZL。