Niclosamide (ethanolamine salt)

产品描述
Niclosamide (Item No. 10649) is an antihelminthic compound that affects mitochondrial metabolism in parasitic worms. It specifically inhibits the signal transducer and activator of transcription 3 (IC50 = 0.25 μM) and stimulates autophagy by reversibly inhibiting mTORC1 signaling (complete inhibition of S6K phosphorylation at 3 μM). Niclosamide ethanolamine is a more water soluble, salt version of niclosamide that has been used to increase energy expenditure and lipid metabolism in mice. At 125 mg/kg/day, niclosamide ethanolamine prevented high-fat diet-induced hepatic steatosis and insulin resistance and improved glycemic control in db/db mice.

更多产品信息，请点击：https://www.caymanchem.com/product/17118
原装进口,Z-His-Phe-OH,Cayman品Pai大包装更优惠!
Cayman公司成立于1980年，在过去20多年的发展过程中，始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂，涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。

温馨提示：不可用于临床ZL。