| 规格： | 1g | 产品价格： | 262.5 |
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| 规格： | 5g | 产品价格： | 661.5 |
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Catalog Number 16228
Molecular Formula C6H6N2O2
Relative Molecular Mass 138.1
CAS Registry Number 3465-72-3
Formulation A crystalline solid
λmax 286 nm
Purity ≥98%
Storage -20°C
SMILES OC(/C=C/C1=CN=CN1)=O
产品描述
trans-Urocanic acid is a major epidermal chromophore for the immunosuppressive effects of UV radiation that is produced in mammalian stratum corneum by the action of histidine ammonialyase on L-histidine. It contributes to the acidification of the surface of the stratum corneum, and its function has been proposed as that of an endogenous sunscreen, endowing a low-level of protection (SPF ~ 1.5) against UV-induced DNA damage and excessive keratinocyte apoptosis. Upon UVB exposure, trans-urocanic acid is converted to the cis isomer, which is known to activate regulatory T cells.
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Cayman公司成立于1980年，在过去20多年的发展过程中，始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂，涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。
温馨提示：不可用于临床ZL。
