规格: | 500μg | 产品价格: | 1459.5 |
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规格: | 1mg | 产品价格: | 2772 |
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Catalog Number 25043
Molecular Formula C29H30D5FN2O5 • 1/2Ca
Relative Molecular Mass 582.7
CAS Registry Number 222412-82-0
Formulation A solid
Purity ≥99% deuterated forms (d1 -d3)
Storage -20°C
SMILES O=C(C1=C(C(C)C)N(CC[C@@H](O)C[C@@H](O)CC([O-])=O)C(C2=CC=C(F)C=C2)=C1C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])NC4=CC=CC=C4.[Ca+2]
产品描述
Atorvastatin-d5 is intended for use as an internal standard for the quantification of atorvastatin (Item No. 10493) by GC- or LC-MS. Atorvastatin is an inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol synthesis, that has IC50 values of 73, 102, and 0.6 nM for HepG2 cells, human fibroblasts, and rat hepatocytes, respectively. Formulations containing atorvastatin have been used in the treatment of hypercholesterolemia and certain dyslipidemias.
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Cayman公司成立于1980年,在过去20多年的发展过程中,始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂,涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。
温馨提示:不可用于临床ZL。