Catalog Number 24768
Synonyms [Arg8]-Vasotocin|AVT
Molecular Formula C43H67N15O12S2 • XCF3COOH
Relative Molecular Mass 1050.2
Formulation A lyophilized powder
Purity ≥95%
Storage -20°C
SMILES NC(CNC([C@H](CCCNC(N)=N)NC([C@@H]1CCCN1C([C@@H](N2)CSSC[C@H](N[H])C(N[C@H](C(N[C@]([C@H](CC)C)([H])C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C2=O)=O)=O)=O)CC3=CC=C(O)C=C3)=O)=O)=O)=O)=O.FC(F)(C(O)=O)F
产品描述
Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor (EC50 = 13 nM for eliciting membrane currents in X. laevis oocytes). Arginine vasotocin is synthesized in the pineal recess and subcommissural organ by ependymal cells and released into the cerebrospinal fluid. It inhibits the induction of sleep and release of hypothalamic releasing and inhibiting hormones. Arginine vasotocin stimulates glycogen phosphorylase α activity and incorporation of phosphate into phosphatidylinositol in rat hepatocytes (EC50s = 0.5 nM and 6.3 nM, respectively). Following a two-minute pulse of arginine vasotocin (1 μM) to neurons isolated from rat suprachiasmatic nuclei, 40.6% of neurons show an increase in firing rate with 11% of the activated neurons responding only to arginine vasotocin and not argipressin (Item No. 24154). Arginine vasotocin (0.1 μg, i.c.v.) activates sexual behavior in male newts and increases the number of clasps per male from saline control levels of 0.6 to 2.9 in an eight-hour period. In rainbow trout, arginine vasotocin (0.1 ng/g, i.c.v.) reduces food intake by over 95% and, after eight hours, increases cortisol and glucose levels by 89% and 27%, respectively.
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Cayman公司成立于1980年,在过去20多年的发展过程中,始终保持着为科研工作者提供高质、优价研究产品的宗旨。该公司目前可以提供13,138 多种生化和免疫试剂,涉及肿瘤、氧化氮、神经学、凋亡、氧化性损伤、内分泌学等研究领域。非常有特色的检测试剂盒包括类花生酸类物质、游离的生物标志、环核苷、激素及氧化氮等。
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