Cellscale微尺度拉伸剪切和纳米压痕仪-代理
微尺度拉伸、压缩、弯曲、剪切和纳米压痕测试系统是一种微型力学测试系统,可以完成其他仪器无法做到的事情。较小的样品,更好的力分辨率,更简单的测试设置和出色的视觉效果。应用包括小组织样品,水凝胶微球,细胞球体和工程微组织。
特点优势:
可对样品进行压缩、拉伸、弯曲和压痕测试; 剪切试验可选
使用0.1μm分辨率的压电致动器实现精度
测试力值范围可在5纳牛(5nN)以下
可选的双轴成像
力分辨率低至10nN
高分辨率CCD成像
集成温控介质浴
功能齐全的用户界面软件,可通过实时反馈进行简单、循环、放松和多模态测试
微尺度拉伸、压缩、弯曲、剪切和纳米压痕测试系统是一种微尺度层面上的拉伸压缩试验系统,能对40-2000 微米的极小试样进行压力载荷测试,测得的数据可以计算出样品的杨氏模量。它可以用来测定各种材料的应力-应变特性,包括组织样品、细胞聚集体、水凝胶和组织工程支架材料等。
发表的文献:
2019 Rapid 3d Bioprinting Of In-Vitro Cardiac Tissue Models Using Human Embryonic Stem Cell-Derived Cardiomyocytes J. Liu, J. He, J. Liu, X. Ma, Q. Chen, N. Lawrence, W. Zhu, Y. Xu, S. Chen
2019使用人类胚胎干细胞衍生心肌细胞快速三维生物打印体外心脏组织模型J.Liu,J.He,J.Liu,X.Ma,Q.Chen,N.Lawrence,W.Zhu,Y.Xu,S.Chen
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2019年用细胞外基质C.Yu,X.Ma,W.Zhu,P.Wang,Kathleen L.Miller,J.Stupin,A.Koroleva Maharajh,A.Hairabedian,S.Chen对人体组织进行无扫描连续3D生物打印
2019 Cell Force-Mediated Matrix Reorganization Underlies Multicellular Network Assembly C. D. Davidson, W. Y. Wang, I. Zaimi, D. K. P. Jayco, B. M. Baker
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2019 A Multimaterial Microphysiological Platform Enabled By Rapid Casting Of Elastic Microwires Y. Zhao, E. Y. Wang, L. H. Davenport, Y. Liao, K. Yeager, G. Vunjak-Novakovic, M. Radisic, B. Zhang
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2019 Significant Adhesion Enhancement Of Bioinspired Dry Adhesives By Simple Thermal Treatment M. Seong, J. Lee, I. Hwang, H. E. Jeong
2019年通过简单热处理显著增强生物激励干胶的附着力M.Seong,J.Lee,I.Hwang,H.E.Jeong
2019 A Scaffold- And Serum-Free Method To Mimic Human Stable Cartilage Validated By Secretome I. Cortes, R. A. M. Matsui, M. S. Azevedo, A. Beatrici, K. L. A. Souza, G. Launay, F. Delolme, J. M. Granjeiro, C. Moali, L. S. Baptista
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2019 A Platform For Generation Of Chamber-Specific Cardiac Tissues And Disease Modeling Y. Zhao, N. Rafatian, N. T. Feric, B. J. Cox, R. Aschar-Sobbi, E. Y. Wang, P. Aggarwal, B. Zhang, G. Conant, K. Ronaldson-Bouchard, A. Pahnke, S. Protze, J. H. Lee, L. D. Huyer, D. Jekic, A. Wickeler, H. E. Naguib, G. M. Keller, G. Vunjak-Novakovic, U. Broeckel, P. H. Backx, M. Radisic
2019年:一个生成心室特异性心脏组织和疾病模型的平台,Y.Zhao,N.Rafatian,N.T.Feric,B.J.Cox,R.Aschar Sobbi,E.Y.Wang,P.Aggarwal,B.Zhang,G.Conant,K.Ronaldson Bouchard,A.Pahnke,S.Protze,J.H.Lee,L.D.Huyer,D.Jekic,A.Wickeler,H.E.Naguib,G.M.Keller,G.Vunjak Novakovic,U.Broeckel、P.H.Backx、M.Radisic
2019 Actomyosin Contractility-dependent Matrix Stretch and Recoil Induces Rapid Cell Migration W. Y. Wang, C. D. Davidson, D. Lin, B. M. Baker
2019肌动球蛋白收缩依赖性基质拉伸和反冲诱导细胞快速迁移W.Y.Wang,C.D.Davidson,D.Lin,B.M.Baker
2019 A 96-Well Culture Platform Enables Longitudinal Analyses Of Engineered Human Skeletal Muscle Microtissue Strength M. E. Afshar, H. Y. Abraha, M. A. Bakooshli, S. Davoudi, N. Thavandiran, K. Tung, H. Ahn, H. Ginsberg, P. W. Zandstra, P. M. Gilbert
2019年,96孔培养平台能够对工程化人体骨骼肌微组织强度进行纵向分析,M.E.Afshar、H.Y.Abraha、M.A.Bakooshli、S.Davoudi、N.Thavandiran、K.Tung、H.Ahn、H.Ginsberg、P.W.Zandstra、P.M.Gilbert
2019 Biomechanical Impact of Localized Corneal Cross-linking Beyond the Irradiated Treatment Area J. N. Webb, E. Langille, F. Hafezi, J. B. Randleman, G. Scarcelli
2019年照射ZL区外局部角膜交联的生物力学影响J.N.Webb,E.Langille,F.Hafezi,J.B.Randleman,G.Scarrelli
2019 Molecularly-ordered Hydrogels with Controllable, Anisotropic Stimulus Response J. M. Boothby, J. Samuel, T. H. Ware
2019年具有可控各向异性刺激响应的分子有序水凝胶J.M.Boothby,J.Samuel,T.H.Ware
2018 Acrylate-Based Materials For Heart Valve Scaffold Engineering R. Santoro, S. Venkateswaran, F. Amandeo, R. Zhang, M. Brioschi, A. Callanan, M. Agrifoglio, C. Banfi, M. Bradley, M. Pesce
2018心脏瓣膜支架工程用丙烯酸酯材料R.Santoro,S.Venkateswaran,F.Amandeo,R.Zhang,M.Brioschi,A.Callanan,M.Agrifoglio,C.Banfi,M.Bradley,M.Pesce
2018 A Microvascularized Tumor-Mimetic Platform For Assessing Anti-Cancer Drug Efficacy S. Pradhan, A.M. Smith, C.J. Garson, I. Hassani, W.J. Seeto, K. Pant, R.D. Arnold, B. Prabhakarpandian, E.A. Lipke
2018用于评估药物LX的微血管化肿瘤模拟平台S.Pradhan,A.M.Smith,C.J.Garson,I.Hassani,W.J.Seeto,K.Pant,R.D.Arnold,B.Prabhakarpandian,E.A.Lipke
2018 Nanoscale Dysregulation Of Collagen Structure-Function Disrupts Mechano-Homeostasis And Mediates Pulmonary Fibrosis M.G. Jones, O.G. Andriotis, J.J.W. Roberts, K. Lunn, V.J. Tear, L.Cao, K. Ask, D.E. Smart, A. Bonfanti, P.Johnson, A. Alzetani, D.E. Davies
2018年胶原结构功能的纳米级失调扰乱了机械稳态,并介导了肺纤维化M.G.Jones,O.G.Andriotis,J.J.W.Roberts,K.Lunn,V.J.Tear,L.Cao,K.Ask,D.E.Smart,A.Bonfanti,P.Johnson,A.Alzetani,D.E.Davies
2018 Extracellular Matrix Surface Regulates Self-Assembly Of Three-Dimensional Placental Trophoblast Spheroids M.K. Wong, S.A. Shawky, A. Aryasomayajula, M.A. Green, T. Ewart, P.R. Selvanganapathy, S. Raha
2018细胞外基质表面调节三维胎盘滋养层球体的自组装M.K.Wong,S.A.Shawky,A.Aryasomayajula,M.A.Green,T.Ewart,P.R.Selvanganapathy,S.Raha
2018 3d Skeletal Muscle Fascicle Engineering Is Improved With Tgf-Β1 Treatment Of Myogenic Cells And Their Co-Culture With Myofibroblasts J. Krieger, B-W. Park, C.R. Lambert, C. Malcuit
2018年,TGF-_1ZL肌源性细胞并与肌成纤维细胞J.Krieger、B-W.Park、C.R.Lambert、C.Malcuit共培养,改善了三维骨骼肌束工程
2018 Combined Use Of Parallel-Plate Compression And Finite Element Modeling To Analyze The Mechanical Properties Of Intact Porcine Lens K. Wang, D.T. Venetsanos, J. Wang, B.K. Pierscionek
2018结合平行板压缩和有限元建模分析完整猪晶状体的力学性能K.Wang,D.T.Venetsanos,J.Wang,B.K.Pierscionek
2018 Mammary Fibroblasts Remodel Fibrillar Collagen Microstructure In A Biomimetic Nanocomposite Hydrogel C. Liu, B. Chiang, D.L. Mejia, K.E. Luker, G.D. Luker, A. Lee
2018年乳腺成纤维细胞在仿生纳米复合水凝胶中重塑纤维胶原微结构C.Liu,B.Chiang,D.L.Mejia,K.E.Luker,G.D.Luker,A.Lee
2018 Hybrid Collagen Alginate Hydrogel As A Platform For 3d Tumor Spheroid Invasion C. Liu, D.L. Mejia, B. Chiang, K.E. Luker, G.D. Luker
2018海藻酸胶原水凝胶作为三维肿瘤球体侵袭平台C.Liu,D.L.Mejia,B.Chiang,K.E.Luker,G.D.Luker
2018 3d Bioprinting Of Hydrogels For Retina Cell Culturing P. Wang, X. Li, W. Zhu, Z. Zhong, A. Moran, W. Wang, K. Zhang, S. Chen
2018年视网膜细胞培养水凝胶3D生物打印王小平、李小丽、朱小珠、钟中安、莫兰、王小平、张小春、陈小春
2018 Matrix Composition In 3-D Collagenous Bioscaffolds Modulates The Survival And Angiogenic Phenotype Of Human Chronic Wound Dermal Fibroblasts P.M. Martin, A. Grant, D.W. Hamilton, L.E. Flynn
2018年三维胶原生物复合物中的基质成分调节人类慢性创伤成纤维细胞的存活和血管生成表型P.M.Martin,A.Grant,D.W.Hamilton,L.E.Flynn
2018 Understanding Interfacial Interactions Of Polydopamine And Glass Fiber And Their Enhancement Mechanisms In Epoxy-Based Laminates H. Zhang, W. Han, J. Tavakoli, Y. Zhang, X. Lin, X. Lu, Y. Ma, Y. Tang
2018了解聚多巴胺和玻璃纤维在环氧基层合板中的界面相互作用及其增强机制H.Zhang,W.Han,J.Tavakoli,Y.Zhang,X.Lin,X.Lu,Y.Ma,Y.Tang
2018 Colloidal Gelatin Microgels With Tunable Elasticity Support The Viability And Differentiation Of Mesenchymal Stem Cells Under Pro‐Inflammatory Conditions B. Sung, J. Krieger, B. Yu, M-H. Kim
2018年具有可调弹性的胶体明胶微凝胶支持炎症前状态下间充质干细胞的存活和分化b.sung,j.krieger,b.yu,m-h.kim
2018 Toward Morphologically Relevant Extracellular Matrix In Vitro Models: 3d Fiber Reinforced Hydrogels A. Williams, J.F. Nowak, R. Dass, J. Samuel, K.L. Mills
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2018 Scaffold-Free, Label-Free And Nozzle-Free Biofabrication Technology Using Magnetic Levitational Assembly V. A. Parfenov, E.V. Koudan, E.A. Bulanova, A.D. Knyazeva, A.A. Gryadunova, O.F. Petrov, V.A. Mironov
2018年无支架、无标签和无喷嘴生物制造技术,采用磁悬浮组件V.A.Parfenov、E.V.Koudan、E.A.Bulanova、A.D.Knyazeva、A.A.Gryadunova、O.F.Petrov、V.A.Mironov
2018 Rapid 3d Bioprinting Of Decellularized Extracellular Matrix With Regionally Varied Mechanical Properties And Biomimetic Microarchitecture X. Ma, C. Yu, P. Wang, W. Xu, X. Wan, C.S.E. Lai, J. Liu, A. K-Maharajh, S. Chen
2018年机械性能和仿生微体系结构不同的去细胞化细胞外基质的快速三维生物打印x.ma,c.yu,p.wang,w.xu,x.wan,c.s.e.lai,j.liu,a.k-maharajh,s.chen
2018 Trans-Differentiation Of Human Adipose-Derived Mesenchymal Stem Cells Into Cardiomyocyte-Like Cells On Decellularized Bovine Myocardial Extracellular Matrix-Based Films Y.E. Arslan, Y.F. Galata, T.S. Arslan, B. Derkus
2018年人脂肪间充质干细胞在去细胞牛心肌细胞外基质膜上转分化为心肌样细胞Y.E.Arslan,Y.F.Galata,T.S.Arslan,B.Derkus
2018 Extracellular Matrix Determines Biomechanical Properties Of Chondrospheres During Their Maturation In Vitro N.P. Omelyanenko, P.A. Karalkin, E.A. Bulanova
2018细胞外基质决定软骨球体外成熟过程中的生物力学特性N.P.Omelyanenko,P.A.Karalkin,E.A.Bulanova
2018 Influence Of Hydrophobic Cross-Linkers On Carboxybetaine Copolymer Stimuli Response And Hydrogel Biological Properties V. Huynh, A. H. Jesmer, M. M. Shoaib, R. G. Wylie
2018疏水交联剂对羧基甜菜碱共聚物刺激响应和水凝胶生物特性的影响V.Huynh,A.H.Jesmer,M.M.Shoaib,R.G.Wylie
2017 A Three-Dimensional Spheroidal Cancer Model Based On Peg-Fibrinogen Hydrogel Microspheres S.Pradhan, J. M. Clary, D. Seliktar, E. A. Lipke
2017年基于PEG纤维蛋白原水凝胶微球S.Pradhan,J.M.Clary,D.Seliktar,E.A.Lipke的三维球状肿瘤模型
2017 Decellularized Adipose Tissue Microcarriers As A Dynamic Culture Platform For Human Adipose-Derived Stem/Stromal Cell Expansion C. Yu, A. Kornmuller, C. Brown, T. Hoare, L.E. Flynn
2017脱细胞脂肪组织微载体作为人类脂肪来源干/基质细胞扩张的动态培养平台C.Yu,A.Kornmuller,C.Brown,T.Hoare,L.E.Flynn
2017 Encapsulation Of Equine Endothelial Colony Forming Cells In Highly Uniform, Injectable Hydrogel Microspheres For Local Cell Delivery W.J. Seeto, Y. Tian, R.L. Winter, F.J. Caldwell, A.A. Wooldridge, E.A. Lipke
2017年将马内皮集落形成细胞封装在高度均匀的可注射水凝胶微球中,用于局部细胞输送W.J.Seeto,Y.Tian,R.L.Winter,F.J.Caldwell,A.A.Wooldridge,E.A.Lipke
2017 Microfluidic Production Of Degradable Thermoresponsive Poly(N-Isopropylacrylamide)-Based Microgels D. Sivakumaran, E. Mueller, T. Hoare
2017年可降解热响应性聚(N-异丙基丙烯酰胺)微凝胶的微流控生产D.Sivakumaran,E.Mueller,T.Hoare
2017 Polysaccharide Hydrogels Support The Long-Term Viability Of Encapsulated Human Mesenchymal Stem Cells And Their Ability To Secrete Immunomodulatory Factors F. Hached, C. Vinatier, P-G. Pinta, P. Hulin, C. Le Visage, P. Weiss, J. Guicheux, A. Billon-Chabaud, G. Grimandi
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2017 Pullulan Microbeads/Si-Hpmc Hydrogel Injectable System For The Sustained Delivery Of Gdf-5 And Tgf-Β1: New Insight Into Intervertebral Disc Regenerative Medicine N. Henry, J. Clouet, A. Fragale, L.Griveau, C. Chedevile, J. Veziers, P. Weiss, J. Le Bideau, J. Guicheaux, C. Le Visage
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2017 Real-Time And Non-Invasive Measurements Of Cell Mechanical Behaviour With Optical Coherence Phase Microscopy D. Gillies, W. Gamal, A. Downes, Y. Reinwald, Y. Yang, A.J. El Haj, P.O. Bagnaninchi
2017年用光学相干相位显微镜对细胞力学行为进行实时无创测量D.Gillies,W.Gamal,A.Downes,Y.Reinwald,Y.Yang,A.J.El Haj,P.O.Bagnaninchi
2017 The Physical Basis Of Coordinated Tissue Spreading In Zebrafish Gastrulation H. Morita, S. Grigolon, M. Bock, S.F.G. Krens, G. Salbreux, C-P. Heisenberg
2017年斑马鱼原肠胚H.Morita,S.Grigolon,M.Bock,S.F.G.Krens,G.Salbreux,C-P.Heisenberg协调组织扩散的物理基础
2017 The Role Of Adhesion Junctions In The Biomechanical Behaviour And Osteogenic Differentiation Of 3d Mesenchymal Stem Cell Spheroids F.E. Griffin, J. Schiavi, T.C. McDevitt, J.P. McGarry, L.M. McNamara
2017粘附连接在三维间充质干细胞球体生物力学行为和成骨分化中的作用F.E.Griffin,J.Schiavi,T.C.McDevitt,J.P.McGarry,L.M.McNamara
2016 An Injectable Hydrogel Prepared Using A Peg/Vitamin E Copolymer Facilitating Aqueous-Driven Gelation J. Zhang, B. Muirhead, M. Dodd, L. Liu, N. Mangiacotte, T. Hoare, S. Sheardown
2016年使用PEG/维生素E共聚物制备的可注射水凝胶促进水驱动凝胶化J.Zhang,B.Muirhead,M.Dodd,L.Liu,N.Mangiacotte,T.Hoare,S.Sheardown
2016 Delivery Of Human Adipose Stem Cells Spheroids Into Lockyballs K.R. Silva, R.A. Rezende, F.D.A.S. Pereira, P. Gruber, M.P. Stuart, A. Ovsianikov, K. Brakke, V. Kasyanov, J.V.L. da Silva, J.M. Granjeiro, L.S. Baptista, V. Mironov
2016年将人类脂肪干细胞球状体输送到Lockyballs K.R.Silva,R.A.Rezende,F.D.A.S.Pereira,P.Gruber,M.P.Stuart,A.Ovsianikov,K.Brakke,V.Kasyanov,J.V.L.Da Silva,J.M.Granjeiro,L.S.Baptista,V.Mironov
2016 Direct Production Of Human Cardiac Tissues By Pluripotent Stem Cell Encapsulation In Gelatin Methacryloyl P. Kerscher, J.A. Kaczmarek, S.E. Head, M. Brazel, W. Seeto, S. Bhattacharya, J. Kim, V. Suppiramaniam, E.A. Lipke
2016年用明胶-甲基丙烯酰P.Kerscher,J.A.Kaczmarek,S.E.Head,M.Brazel,W.Seeto,S.Bhattacharya,J.Kim,V.Suppiramanim,E.A.Lipke中的多能干细胞包埋直接生产人类心脏组织
2016 Mineral Particles Modulate Osteo-Chondrogenic Differentiation Of Embryonic Stem Cell Aggregates Y. Wang, X. Yu, C. Baker, W.L. Murphy, T.C. McDevitt
2016年矿物质颗粒调节胚胎干细胞聚集体的骨软骨分化王晓明,俞晓明,贝克,墨菲,麦克德维特
2016 Peg-Fibrinogen Hydrogels For Three-Dimensional Breast Cancer Cell Culture S. Pradhan, I. Hassani, W.J. Seeto, E. A. Lipke
2016聚乙二醇纤维蛋白原水凝胶用于三维乳腺癌细胞培养S.Pradhan,I.Hassani,W.J.Seeto,E.A.Lipke
2016 Reactive Eletrospinning Of Degradable Poly(Oligoethylene Glycol Methacrylate)-Based Nanofibrous Hydrogel Networks F. Xu, H. Sheardown, T. Hoare
2016可降解聚(甲基丙烯酸低聚乙二醇酯)基纳米纤维水凝胶网络的反应性电纺丝f.xu,h.sheardown,t.hoare
2015 Burr-Like, Laser-Made 3d Microscaffolds For Tissue Spheroid Encagement P. Danilevicius, R.A. Rezende, F.D.A.S. Pereira, A. Selimis, V. Kasyanov, P.Y. Noritomi, J.V.L. da Silva, M.Chatzinikolaidou, M. Farsari, V. Mironov
2015 Burr-like,Laser-made 3D微胶囊,用于组织球体包裹P.Danilevicius,R.A.Rezende,F.D.A.S.Pereira,A.Selimis,V.Kasyanov,P.Y.Noritomi,J.V.L.Da Silva,M.Chatzinikolaidou,M.Farsari,V.Mironov
2014 Mesenchymal Morphogenesis Of Embryonic Stem Cells Dynamically Modulates The Biophysical Microtissue Niche M.A. Kinney, R.Saeed, T.C. McDevitt
2014胚胎干细胞间充质形态发生动态调节生物物理微组织生态位M.A.Kinney,R.Saeed,T.C.McDevitt
2013 Alginate Encapsulation Parameters Influence The Differentiation Of Microencapsulated Embryonic Stem Cell Aggregates Wilson, J.L., Ali Naijia, M., Saeed, R., McDevitt, T.C.
2013海藻酸钠包埋参数影响微囊化胚胎干细胞聚集体的分化Wilson,J.L.,Ali Naijia,M.,Saeed,R.,McDevitt,T.C.
2012 Stiffening Of Human Mesenchymal Stem Cell Spheroid Mircoenvironments Induced By Incorporation Of Gelatin Microparticles P. R. Baraniak, M.T. Cooke, R. Saeed, M.A. Kinney, K.M. Fridley, T.C. mcDevitt
2012年:明胶微粒P.R.Baraniak,M.T.Cooke,R.Saeed,M.A.Kinney,K.M.Fridley,T.C.McDevitt对人间充质干细胞球体微环境的强化作用
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