douglas Oryx 蛋白结晶机器人/结晶系统

Oryx8 is the flagship Douglas Instruments protein crystallization robot. It can set up sitting drops down to 100 + 100 nl and up to 2 + 2 µl for 96 wells. For hanging drop experiments up to five drops can be set up per cover slide, with volumes up to 8 + 8 µl.  (For screening experiments the reservoirs must be predispensed by some other method such as a 12-channel pipette. For optimization experiments the reservoirs are filled automatically.)  Standard screening, additive and microseeding experiments are included as well as microbatch-under-oil screens (also down to 100 + 100 nl).  Optimization experiments can be carried out  using up to 7 ingredients with full pH control, including multi-variate designs such as the Central Composite. In addition, quick-and-easy 2-D grid optimizations with up to 4 ingredients can be carried out in a few minutes. 

Oryx4 is the product for those users who do not want to do multi-variate optimization. As with the Oryx8, it performs standard screening, additive, microseeding, sitting drop and hanging drop experiments and microbatch-under-oil screens (also down to 100+100 nl). Oryx4 can be upgraded to Oryx8 if multi-variate optimization becomes a requirement.

OryxNano is a compact option which has the capability of the Oryx4, except for hanging drop, microbatch and additive experiments. OryxNano can do quick-and-easy 2-D grid optimizations with up to 4 ingredients.

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设备来源：原装进口。

技术参数：

1.该仪器是自动进行蒸汽扩散法的蛋白质结晶学研究系统，将用于高通量蛋白质结晶条件筛选。

2.Z小蛋白样品用量0.1μl，蛋白样品损耗小于2%。

3.可同时设置一种以上的蛋白样品。

4.样品处理板型：96孔板，SBS板，非SBS板。

5.PC机控制。

6.系统自带样品清洗功能，每次实验可自动清洗枪头。

7.运行过程中，更换样品时，不需要更换枪头。

8.运行成本：一个96孔板平均成本低于1美元。

9.所有消耗品（包括试剂，96孔板）都开放，兼容性强。

10.枪头点样精度必须要控制在（±0.1mm）以内。

11.仪器的结晶板开放，国内可以购买，兼容性强。

12.实现高精度连续批量处理结晶样品，避免人工重复劳动，极大地避免人为失误和减少交叉污染，精度：100nl CV<2%.

13.大大加快蛋白质结晶条件筛选过程，可在数分钟内筛选近百种结晶条件。

14.可以设置在下降到100±100 NL和2 + 2µL 96孔。

15.悬滴试验达五滴可以设置每个滑盖，量高达8 + 8µL。

16. 能够进行微晶种矩阵筛选（MMS）。

17. 优化实验可以使用Z多7个成分全pH值进行控制，包括多变量设计如星点。

18.快速和简单的二维网格优化，高达4的成分，可以在几分钟内进行。

19.标准的筛选、添加剂和microseeding结果以及microbatch下油屏幕（也下降到100±100 NL）。

20.蒸汽扩散法生长晶体。

21. 同时能采用三种方法：坐滴、悬滴、油滴