IFN alpha-IFNAR-IN-1 (hydrochloride)

IFN alpha-IFNAR-IN-1 (hydrochloride)产品描述：IFN alpha-IFNAR-IN-1 hydrochloride is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR; inhibit MVA-induced IFN-α responses by BM-pDCs (IC50=2-8 uM). IC50 value: Target: IFN alpha-IFNAR interaction inhibitor IFN alpha-IFNAR-IN-1 specifically inhibits MVA-induced IFN-α responses by BM-pDCs. IFN alpha-IFNAR-IN-1 inhibited the IFN-α responses that were elicited after treatment with CpG2216, stimulation with poly(I:C), and infection with VSV-M2, whereas the total IL-12 production was notably less affected under those conditions. IFN alpha-IFNAR-IN-1 exerts immunosuppressive activity by the direct interaction with IFN-α [1].


公司介绍：MedChemExpress(MCE)专注于各种YZ剂、激动剂、API及化合物库，总部位于美国新泽西，分别在瑞典和上海设有欧洲区子公司和亚洲区总代理，营销网点遍及20多个国家地区。MCE经过多年努力已成为生物活性小分子领域的供应商， 产品涵盖癌症、神经科学、抗感染、表观遗传学等20个热门研究领域，PI3K、MAPK等近千个细分靶点，超过4000个活性小分子化合物现货，以及GPCR、API、离子通道等超过20种不同类型的化合物库，同时提供从毫克到千克的专业定制合成服务。
MCE 对每批产品都进行严格的LCMS和NMR检验，其产品已被近万名客户广泛使用并发表大量文章、专利；
MCE 定期增加各领域热门YZ剂、激动剂，不断扩增已有化合物库，以满足的科研需求；
数千种产品在上海有充足备货，24-48小时内送达客户；
大量产品提供免费SY装； 已为多个知名企业、院校构建各种定制型化合物库。

产品链接：www.medchemexpress.cn/ifn-alpha-ifnar-in-1-hydrochloride.html