多非利特 Dofetilide
Content : ≥98%
化学名称 :
4-(2-氯乙氧基)硝基苯
2-[4-硝基苯氧基]氯乙烷
cas: 115256-11-6
分子式 : C19H27N3O5S2
Molecular formula :C19H27N3O5S2
分子量:441.56
Molecular weight :441.56
外观:白色晶体粉末
Appearance:the white crystal powder
标准:企业标准
Standard:Enterprise
规格:原料药
Specifications:pharmaceutical raw materials
密度:5.13E-15mmHg at 25°C
Density : 5.13E-15mmHg at 25°C
闪点:325.2°C
Flash Point: 325.2°C
Synonyms:
Methanesulfonamide ;
Dofetilide;
N-[4-[2-[methyl[2-[4-[(methylsulfonyl)amino]phenoxy]ethyl]amino]ethyl]phenyl]
用途 :选择性钾通道激动剂,为Ⅲ类抗心律失常药,用于心房纤颤和心房扑动。
Use :The circulatory system of drug ;Anti-arrhythmic drugs of Ⅲ type;Used for atrial fibrillation and atrial flutter
化学性质:从乙酸乙酯-甲醇(10:1)结晶,熔点147~149℃;从己烷-乙酸乙酯结晶,熔点151~152℃; 熔点161℃,pKa 7.0,9.0,9.6。分配系数(Ph=7.4):0.96。