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赭曲霉毒素 霉菌毒素 肾毒素 Ochratoxin A 303-47-9
【产品简介】
霉菌毒素。发霉的食品和饲料的天然污染物。它有一些毒副作用,最突出的是肾毒性。免疫,遗传毒性,致畸,致癌。促进脂质过氧化。加上直接通过DNA加合物形成醌氧化DNA损伤诱导。
Mycotoxin. Natural contaminant of mouldy food and feed. It has a number of toxic effects, the most prominent being nephrotoxicity. Immunosuppressive, genotoxic, teratogenic and carcinogenic. Stimulates lipid peroxidation. Induces oxidative DNA lesions coupled with direct DNA adducts via quinone formation.
【产品说明】
Formula:
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C20H18ClNO6
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MW:
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403.8
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Source:
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Isolated from Aspergillus ochraceus
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CAS:
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303-47-9
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MI:
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14: 6740
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RTECS:
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AY4375000
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Purity:
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≥98% (HPLC, TLC)
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Appearance:
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White to off-white crystalline powder.
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Hazard:
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MAY BE CARCINOGENIC.
MAY BE MUTAGENIC.
MAY BE TERATOGENIC.
VERY TOXIC.
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Solubility:
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Soluble in methanol (10mg/ml). .
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Long Term Storage:
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+4°C
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【产品相关文献】
Ochratoxin A: An overview on toxicity and carcinogenicity in animals and humans: A. Pfohl-Leszkowicz & R. A. Manderville; Mol. Nutr. Food Res. 51, 61 (2007), (Review), Abstract;
Toxicokinetics and toxicodynamics of ochratoxin A, an update: D. Ringot, et al.; Chem. Biol. Interact. 159, 18 (2006), (Review), Abstract;
How aspartame prevents the toxicity of ochratoxin A: E.E. Creppy, et al.; J. Toxicol. Sci. 23 Supp. 2, 165 (1998), Abstract;
Toxicity and metabolism of ochratoxin A: J. Fink-Gremmels, et al.; Nat. Toxins 3, 214 (1995), Abstract;
Effect of superoxide dismutase and catalase on the nephrotoxicity induced by subchronical administration of ochratoxin A in rats: I. Baudrimont, et al.; Toxicology 89, 101 (1994), Abstract;
Role of cytochrome P-450 in ochratoxin A-stimulated lipid peroxidation: R.F. Omar, et al.; J. Biochem. Toxicol. 6, 203 (1991), Abstract;
Mechanism of ochratoxin A stimulated lipid peroxidation: R.F. Omar, et al.; Biochem. Pharmacol. 40, 1183 (1990),Abstract;
Lipid peroxidation as a possible cause of ochratoxin A toxicity: A.D. Rahimtula, et al.; Biochem. Pharmacol. 37, 4469 (1988), Abstract;
Ochratoxin A, a toxic metabolite produced by Aspergillus ochraceus Wilh: K.J. van der Merwe, et al.; Nature 205, 112 (1965), Abstract;
【订货信息】
货号
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品名
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规格
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ALX-630-089-M001
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Ochratoxin A
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1mg
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ALX-630-089-M005
|
Ochratoxin A
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5mg
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ALX-630-089-M025
|
Ochratoxin A
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25mg
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