美国Seracare HIV血清质控盘（Qualification Panels）

美国Seracare HIV血清质控盘（Qualification Panels）

广州健仑生物科技有限公司

SeraCare Life Sciences公司主要在美国、欧洲和亚洲提供促进人类和动物诊断和ZL学的探索、开发和生产的产品和服务。其业务分为两个部分：诊断和生物制药产品和生物服务。诊断和生物制药产品部门生产和销售诊断和控制面板产品，用于测试传染性疾病的临床实验室及员工培训和能力测试。生物服务部门提供生物银行、来样加工和测试服务。

美国SeraCare收购BBI公司，即原BBI血清盘已经改名为SeraCare血清盘。

其产品包括有：传染病阳性质控品、疾病标准品、细菌阳性质控品、人血清白蛋白、人伽马球蛋白、牛血清白蛋白、血清盘、人血浆、人血清。

SeraCare的血清盘包括：HIV-1转化盘、HIV性能盘、HBV转化盘、HBV性能盘、HCV转化盘、HCV性能盘、弓形虫性能盘、线性盘和质控盘等等。

我司还提供其它进口或国产试剂盒：登革热、疟疾、流感、A链球菌、合胞病毒、腮病毒、乙脑、寨卡、黄热病、基孔肯雅热、克锥虫病、违禁品滥用、肺炎球菌、军团菌、化妆品检测、食品安全检测等试剂盒以及日本生研细菌分型诊断血清、德国SiFin诊断血清、丹麦SSI诊断血清等产品欢迎致电。

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美国Seracare HIV血清质控盘（Qualification Panels）

美国Seracare HIV血清质控盘（Qualification Panels）

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【公司名称】 广州健仑生物科技有限公司

【市 场 部】 13802525278 020-82574011  杨永汉

【公司传真】 020-32206070

【腾讯Q Q】 2042552662

【公司地址】 广州清华科技园创新基地番禺石楼镇创启路63号二期2幢101-103室

线粒体是人类细胞将糖转化成能量的重要工厂。西奈山伊坎医学院的科学家们开发了一种新测序技术，可以帮助人们理解线粒体基因对个体患病风险的影响，比如糖尿病、心脏病和癌症。这项研究发表在近期的Nucleic Acids Research杂志上。
在年龄、体重和坏习惯(比如吸烟)相同的人中，有些会生病有些却不会。研究者们一直对这一点感到迷惑，并尝试通过饮食和核基因来确定个体的患病风险。但这样的分析遗漏了线粒体基因(mtDNA)的差异，mtDNA遗传自我们的母亲，每个细胞都有这样的DNA。
近年来研究表明，线粒体发生错误会引起严重的疾病。然而由于mtDNA的异质性很大，分析mtDNA变异对个体疾病风险的影响非常复杂。
这项研究展示了可以准确鉴定mtDNA异质性的测序技术，Mseek。细胞里的mtDNA含量很少，过去这方面一直没有什么进展。人们意识到了mtDNA的异质性，但却无法再单细胞水平上建立决定性的理论。
“研究者们一直在寻找能够准确测序mtDNA的低成本方法，”西奈山伊坎医学院的助理教授Ravi Sachidanandam博士说。“现在我们做到了这一点。Mseek可以鉴定线粒体中的功能紊乱，使mtDNA成为了有用的生物学指标。此外，人们还可以将mtDNA作为潜在的靶标，ZL癌症和多种遗传疾病。”
据Dr. Sachidanandam介绍，新测序技术达到了KQ的灵敏性、特异性和测序深度，能够得到高纯度的mtDNA，检测不同版本的mtDNA或mtDNA变体。
Mseek主要是利用酶清除细胞核DNA，只留下线粒体DNA进行测序。研究人员将Mseek用于多个细胞系，鉴定了不同细胞样本中的mtDNA“指纹”。他们还通过追踪mtDNA变体发现，mtDNA异质性在单细胞水平上是稳定维持的。

Mitochondria are important plants where human cells convert sugar into energy. Scientists at the Icahn School of Medicine in Mount Sinai have developed a new sequencing technology that can help people understand the impact of mitochondrial genes on individual risk factors such as diabetes, heart disease and cancer. This study was published in the recent issue of Nucleic Acids Research.
Some people who are the same in age, weight, and bad habits (such as smoking) are sick but not others. Researchers have always been puzzled by this and tried to determine the risk of the individual through diet and nuclear genes. But such an analysis missed the difference in mitochondrial genes (mtDNA) that we inherited from our mother, and each cell has such DNA.
Recent studies have shown that mistakes in mitochondria can cause serious diseases. However, due to the heterogeneity of mtDNA, it is very complicated to analyze the impact of mtDNA mutation on individual disease risk.
This study shows the first sequencing technology that can accurately identify mtDNA heterogeneity, Mseek. The mtDNA content in the cells is very small, and there has been little progress in this area. People are aware of the heterogeneity of mtDNA but can no longer establish deterministic theories at the single cell level.
“Investigators are always looking for low-cost methods that can accurately sequence mtDNA,” said Dr. Ravi Sachidanandam, an assistant professor at Icahn Medical School in Mount Sinai. "Now we have done this. Mseek can identify functional disorders in mitochondria, making mtDNA a useful biological indicator. In addition, people can use mtDNA as a potential target for the treatment of cancer and many genetic diseases."
According to Dr. Sachidanandam, the new sequencing technology has achieved unprecedented sensitivity, specificity, and sequencing depth, enabling high-purity mtDNA to detect different versions of mtDNA or mtDNA variants.
Mseek uses enzymes to remove nuclear DNA, leaving only mitochondrial DNA for sequencing. The researchers used Mseek for multiple cell lines and identified mtDNA "fingerprints" in different cell samples. They also found that by tracking mtDNA variants, mtDNA heterogeneity was stable at the single cell level.