SC-7862 TNF-R2 (H-202)抗体

抗体 名：TNF-R2 (H-202)抗体
规格：200ug
Santa Cruz是美国也是世界上Z大的抗体生产厂家，提供抗体种类多达两万多种，几乎覆盖了目前生命科学研究的各个新领域，其每种抗体又有多个克隆可选择，并有对应蛋白标准品及相关产品，为免疫学研究工作提供了极大的方便。
产品介绍：TNF-R2 Antibody (H-202) is a rabbit polyclonal IgG provided at 200 µg/ml
epitope corresponding to amino acids 260-461 mapping at the C-terminus of TNF-R2 of human origin
recommended for detection of TNF-R2 of mouse, rat and human origin by WB, IP, IF and ELISA
See 12 citations for TNF-R2 抗体 (H-202)
TNF-R2 (H-202)抗体基因信息：
Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated through two distinct cell surface receptors (1). These receptors, designated TNF-R1 and TNF-R2, are expressed on most cell types (1,2). The majority of TNF functions are primarily mediated through TNF-R1, while signaling through TNF-R2 occurs less extensively and is confined to cells of the immune system (1). Both of these proteins belong to the growing TNF and nerve growth factor (NGF) receptor superfamily, which includes FAS, CD30, CD27 and CD40 (3). The members of this superfamily are type I membrane proteins that share sequence homology confined to the extracellular region (2). TNF-R1 shares a motif termed the “death domain” with FAS and three structurally unrelated signaling proteins, TRADD, FADD and RIP (1,3–8). This death domain is required for transduction of the apoptotic signal (9).
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