透明质酸-丙烯酸盐，Hyaluronate-Acrylate 试剂知识 常用

Hyaluronate-Acrylate, MW 10kDa 透明质酸-丙烯酸盐
Hyaluronate-Acrylate, MW 50kDa 透明质酸-丙烯酸盐
Hyaluronate-Acrylate, MW 250kDa ​透明质酸-丙烯酸盐

透明质酸（hyaluronic acid，HA），又名玻璃酸，是一种独特的线性大分子酸性粘多糖，由葡萄糖醛酸和N-乙酰氨基葡萄糖的双糖单位反复交替连接而成。与其他天然粘多糖不同，HA分子内不含硫酸基团，也不与蛋白质共价结合，能以自由链形式在体内游离存在。HA（透明质酸）广泛分布于动物和人体结缔组织外基质中，在眼玻璃体、脐带、皮肤、软骨和滑液中含量较高，血清中含量ZD。依据组织来源不同，分子量变化于10⁵-10⁷之间。
Hyaluronic acid (hyaluronic acid, HA), also known as hyaluronic acid, is a linear molecule unique acidic polysaccharide, composed of glucuronic acid and N- acetyl glucosamine disaccharide units alternately connected together. Different from other natural polysaccharides, the HA molecules do not contain sulfate groups, and are not covalently bound to proteins. HA (Hyaluronate) is widely distributed in the extracellular matrix of animal and human connective tissue, which is the highest in the vitreous, umbilical cord, skin, cartilage and synovial fluid. According to the different source of tissue, the molecular weight changes between 10⁵-10⁷.
HA（透明质酸）的酯化可在其羧基及羟基上进行，一般以羧基的酯化较为常见。通过酯化反应，在不改变HA（透明质酸）主链前提下，HA（透明质酸）的理化性质，如聚合物稳定性、水溶性以及生物学性质，如细胞黏附能力将得到很大程度改变。许多非ZL活性的醇，如乙醇、丙醇、芳香醇、以及ZL活性的醇如类固醇，都可通过酯化反应连接到HA（透明质酸）主链上。所形成酯的水溶性取决于参与醇化反应醇的类型和酯化度。
The esterification of HA (Hyaluronate) can be carried out on carboxyl and hydroxyl groups. Through esterification reaction, without changing the HA (Hyaluronate) chain under the premise of HA (Hyaluronate) physicochemical properties, such as polymer stability, water solubility and biological properties, such as cell adhesion ability will be greatly changed. Many non active alcohols, such as ethanol, propanol, aromatic alcohols, and therapeutically active alcohols, such as steroids, can be attached to the HA (Hyaluronate) backbone by esterification. The formation of ester water solubility depends on the type of alcohol in the synthesis reaction and degree of esterification.
西安瑞禧生物科技有限公司实验室ZX推出了一批透明质酸纳衍生物，分子量从2000-200万不等，末端带有各种活性修饰基团。
透明质酸分子量有：2000/5000/10000/20000/50000/100000/200000/500000/700000/1000000
透明质酸可接基团：NH2/COOH/NHS/MAL/N3/Biotin/Acrylate/SH/FITC/RB/PEG
我公司还可以提供透明质酸和PEG的共聚物，PEG末端带不同活性基团。
详细产品列表：
Hyaluronate-Biotin, MW 10kDa
Hyaluronate-Biotin, MW 20kDa
Hyaluronate-Biotin, MW 250kDa
Hyaluronate-Biotin, MW 500kDa
 
Hyaluronate-Mono-Biotin, MW 10kDa
Hyaluronate-Mono-Biotin, MW 50kDa
Hyaluronate-Mono-Biotin, MW 500kDa
Hyaluronate-Mono-Biotin, MW 1,500kDa
 
Biotin-Hyaluronate-Fluorescein, MW 10kDa
Biotin-Hyaluronate-Fluorescein, MW 20kDa
Biotin-Hyaluronate-Fluorescein, MW 250kDa
Biotin-Hyaluronate-Fluorescein, MW 2,500kDa
 
Hyaluronate-Rhodamine, MW 5kDa
Hyaluronate-Rhodamine, MW 10kDa
Hyaluronate-Rhodamine, MW 20kDa
Hyaluronate-Rhodamine, MW 50kDa
 
Hyaluronate-Fluorescein, MW 2kDa
Hyaluronate-Fluorescein, MW 10kDa
Hyaluronate-Fluorescein, MW 50kDa
 
Hyaluronate-AMCA, MW 20kDa
Hyaluronate-AMCA, MW 250kDa
Hyaluronate-AMCA, MW 500kDa
 
Hyaluronate-Acrylate, MW 10kDa
Hyaluronate-Acrylate, MW 50kDa
Hyaluronate-Acrylate, MW 250kDa
 
Hyaluronate-Aldehyde, MW 50kDa
Hyaluronate-Aldehyde, MW 250kDa
Hyaluronate-Aldehyde, MW 1,000kDa
 
Hyaluronate-Amine, MW 10kDa
Hyaluronate-Amine, MW 50kDa
Hyaluronate-Amine, MW 250kDa
 
Hyaluronate-Epoxide, MW 50kDa
Hyaluronate-Epoxide, MW 1,000kDa
Hyaluronate-Epoxide, MW 2,500kDa
 
Hyaluronate-Maleimide, MW: 5k
Hyaluronate-Maleimide, MW: 20k
Hyaluronate-Maleimide, MW: 50k
 
Hyaluronate-NHS, MW 10kDa
Hyaluronate-NHS, MW 50kDa
Hyaluronate-NHS, MW 1,000kDa
 
Hyaluronate-Hydrazide, MW 10kDa
Hyaluronate-Hydrazide, MW 20kDa
Hyaluronate-Hydrazide, MW 100kDa
 
Hyaluronate-Thiol, MW 10kDa
Hyaluronate-Thiol, MW 20kDa
Hyaluronate-Thiol, MW 50kDa
 
透明质酸钠和聚乙二醇共聚产品末端带各种活性基团产品列表：
Hyaluronate-PEG, HA MW 2k & PEG MW 2k
Hyaluronate-PEG, HA MW 5k & PEG MW 2k
Hyaluronate-PEG, HA MW 10k & PEG MW 2k
Hyaluronate-PEG, HA MW 50k & PEG MW 2k
Hyaluronate-PEG, HA MW 250k & PEG MW 2k
 
Hyaluronate-PEG, HA MW 2k & PEG MW 5k
Hyaluronate-PEG, HA MW 5k & PEG MW 5k
Hyaluronate-PEG, HA MW 10k & PEG MW 5k
Hyaluronate-PEG, HA MW 50k & PEG MW 5k
Hyaluronate-PEG, HA MW 250k & PEG MW 5k
 
Hyaluronate-PEG-NH2, HA MW 2k & PEG MW 2k
Hyaluronate-PEG-NH2, HA MW 5k & PEG MW 2k
Hyaluronate-PEG-NH2, HA MW 10k & PEG MW 2k
Hyaluronate-PEG-NH2, HA MW 50k & PEG MW 2k
Hyaluronate-PEG-NH2, HA MW 250k & PEG MW 2k
 
Hyaluronate-PEG-MAL, HA MW 2k & PEG MW 2k
Hyaluronate-PEG-MAL, HA MW 5k & PEG MW 2k
Hyaluronate-PEG-MAL, HA MW 10k & PEG MW 2k
Hyaluronate-PEG-MAL, HA MW 50k & PEG MW 2k
Hyaluronate-PEG-MAL, HA MW 250k & PEG MW 2k
Hyaluronate-PEG-NHS, HA MW 2k & PEG MW 2k
Hyaluronate-PEG-NHS, HA MW 5k & PEG MW 2k
Hyaluronate-PEG-NHS, HA MW 10k & PEG MW 2k
Hyaluronate-PEG-NHS, HA MW 50k & PEG MW 2k
Hyaluronate-PEG-NHS, HA MW 250k & PEG MW 2k
 
Hyaluronate-PEG-Folate, HA MW 2k & PEG MW 2k
Hyaluronate-PEG-Folate, HA MW 5k & PEG MW 2k
Hyaluronate-PEG-Folate, HA MW 10k & PEG MW 2k
Hyaluronate-PEG-Folate, HA MW 50k & PEG MW 2k
Hyaluronate-PEG-Folate, HA MW 250k & PEG MW 2k
如您需要，我司还可提供各种不同活性基团的产品，欢迎定制选购。
 
以上资料源于西安瑞禧生物科技有限公司
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