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FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.
FIIN-2 is an irreversible inhibitor of FGFR1-4 with IC50 values of 3.1, 4.3, 27, and 45 nM, respectively.
FIIN-3 is an irreversible inhibitor of FGFR1-4 with IC50s of 13, 21, 31, and 35 nM, respectively.
BAY 11-7082 is an irreversible inhibitor of IKKα and phosphorylation of cytokine-inducible IκBα (nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-α, NFKBIA; IC50=10 μM).
Irreversible inhibitor of GABA transaminase
Abcam优势服务 货号:ab146721,Irreversible inhibitor of GABA transaminase. 1 ml water soluble pack.
Abcam优势服务 货号:ab120310,Irreversible inhibitor of GABA transaminase
CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR with IC50 of 370_addition_/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
Acetohydroxamic acid is a potent and irreversible inhibitor of bacterial and plant urease and also used as adjunctive therapy in chronic urinary infection.
CL-387785(EKI785; WAY-EKI 785) is an irreversible inhibitor of EGFR with IC50 of 370(addition)/-120 pM; is able to overcome resistance caused by the T790M mutation on a functional level.
Abcam优势服务 货号:ab144779,Potent irreversible inhibitor of low Km mitochondrial aldehyde dehydrogenase (ALDH)
Neratinib (HKI-272) is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively.
Dacomitinib(PF299804) is a potent, orally available, irreversible tyrosine kinase HER 1 (EGFR), HER2 and HER4 inhibitor with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2 and ERBB4, respectively.
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