重组人骨形态发生蛋白4，有活性的/BMP 4 Human, Active_详细资料

产品信息 重组人骨形态发生蛋白4，有活性的/BMP 4 Human, Active 产品编号:CYT-081产品名称:重组人骨形态发生蛋白4，有活性的/BMP 4 Human, Active 产品规格:2ug/10ug/100ug Catalogue Number CYT-081 Synonyms BMP4, ZYME, BMP2B, BMP2B1. Introduction The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5 untranslated region of this gene has been described and three variants are described, all encoding an identical protein. Description BMP-4 Human Recombinant produced in HEK cells is a glycosylated disulfide linked homodimer, having a total molecular weight of 34kDa. The BMP-4 is purified by proprietary chromatographic techniques. Source HEK. Physical Appearence Sterile Filtered White lyophilized (freeze-dried) powder. Formulation The BMP4 was lyophilized from 1mg/ml in 1xPBS. Solubility It is recommended to reconstitute the lyophilized BMP-4 in sterile 4mM HCl containing 0.1% endotoxin-free recombinant HSA. Stability Lyophilized BMP4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BMP-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. Purity Greater than 95% as obsereved by SDS-PAGE. Biological Activity The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line) and is typically 2-10ng/ml. Usage ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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Catalogue Number	CYT-081
Synonyms	BMP4, ZYME, BMP2B, BMP2B1.
Introduction	The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5 untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
Description	BMP-4 Human Recombinant produced in HEK cells is a glycosylated disulfide linked homodimer, having a total molecular weight of 34kDa. The BMP-4 is purified by proprietary chromatographic techniques.
Source	HEK.
Physical Appearence	Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation	The BMP4 was lyophilized from 1mg/ml in 1xPBS.
Solubility	It is recommended to reconstitute the lyophilized BMP-4 in sterile 4mM HCl containing 0.1% endotoxin-free recombinant HSA.
Stability	Lyophilized BMP4 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BMP-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity	Greater than 95% as obsereved by SDS-PAGE.
Biological Activity	The specific activity was determined by the dose dependent induction of alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line) and is typically 2-10ng/ml.
Usage	ProSpecs products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.