Human BMP-13/CDMP-2/重组人骨形态发生蛋白-13/CDMP-2

Human BMP-13/CDMP-2/重组人骨形态发生蛋白-13/CDMP-2
产品编号:100-137 产品名称:Human BMP-13/CDMP-2/重组人骨形态发生蛋白-13/CDMP-2 产品规格:50μg
Description: BMP-13 is expressed in hypertrophic chondrocytes during embryonic development of long bones. Continued postnatal expression of BMP-13 in articular cartilage suggests that it plays a regulatory role in the growth and maintenance of articular cartilage. Adenovirus-mediated BMP-13 gene transfer to rabbit bone marrow stem cells have been reported to augment periosteal repair of osteochondral defects. The functional form of BMP-13/CDMP-2 is a disulfide-linked homodimer of two 120 amino acid polypeptide chains. This 27.5 kDa protein is obtained by proteolytic processing of a biologically inactive precursor protein of 97.7 kDa. Recombinant human BMP-13/CDMP-2 is a 27.0kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
Source: E. coli
Molecular Weight: 27 kDa
Purity: > 95% by SDS-PAGE
Endotoxin level/内毒素水平: < 0.1 ng per μg of BMP-13
Stabilizer: none
Formulation: lyophilized
Biological Activity: The ED50 was determined by its ability to induce alkaline phosphatase production by ATDC-5 chondrogenic cells in the range of 2.0-3.0 μg/ml.
Reconstitution: The human BMP-13 should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20°C.
Stability: The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C. Reconstituted human BMP-13 should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles.
Usage: Human BMP-13 offered for research use. Not for drug use. Not for human use.