ID:T1829
PURITY:0.98
Formula:C17H18N6
MolWt:306.37
Appearance:白色粉末
Solubility:G4DMSO 60 mg/mL
Bioactivity:Ruxolitinib(INCB018424) is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3.
Status:
Pathways:JAK/STAT Signaling
Target:JAK inhibitor
Receptor:JAK1/2
温馨提示:不可用于临床ZL。