Acamprosate calcium阿坎酸钙

ID：T1673

PURITY：0.98

Formula：C10H20CaN2O8S2

MolWt：400.48

Appearance：白色粉末

Solubility：G410 mM in Water and DMSO

Bioactivity：Acamprosate, also known by the brand name Campral™, is a drug used for treating alcohol dependence. Acamprosate is thought to stabilize the chemical balance in the brain that would otherwise be disrupted by alcoholism, possibly by blocking glutaminergic N-methyl-D-aspartate receptors, while gamma-aminobutyric acid type A receptors are activated. Reports indicate that acamprosate only works with a combination of attending support groups and abstinence from alcohol. Certain serious side effects include allergic reactions, irregular heartbeats, and low or high blood pressure, while less serious side effects include headaches, insomnia, and impotence. Acamprosate should not be taken by people with kidney problems or allergies to the drug.

Status：USAN, INN, BAN

Pathways：Neuroscience

Target：GABAR modulator

Receptor：GABA-A receptor