Sunitinib Malate苏尼替尼苹果酸盐

ID：T0374

PURITY：0.98

Formula：C22H27FN4O2

MolWt：532.56

Appearance：橘黄色粉末

Solubility：G4Soluble in DMSO

Bioactivity：Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor. Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models.

Status：USP

Pathways：Tyrosine Kinase/Adaptors

Target：c-Kit inhibitor; PDGFR inhibitor; VEGFR inhibitor

Receptor：c-Kit;PDGFRβ;VEGFR2