ID：T0083
PURITY：0.98
Formula：C24H30O6
MolWt：414.49
Appearance：白色粉末
Solubility：G4DMSO <1 mg/mL; Water <1 mg/mL
Bioactivity：Eplerenone, an aldosterone receptor antagonist similar to spironolactone, has been shown to produce sustained increases in plasma renin and serum aldosterone, consistent with inhibition of the negative regulatory feedback of aldosterone on renin secretion. The resulting increased plasma renin activity and aldosterone circulating levels do not overcome the effects of eplerenone. Eplerenone selectively binds to recombinant human mineralocorticoid receptors relative to its binding to recombinant human glucocorticoid, progesterone and androgen receptors.
Status：USP
Pathways：Endocrinology/ Hormones
Target：Mineralocorticoid Receptor Antagonist LIPT1 Multivitamin uptake inhibitor;VB
Receptor：Mineralocorticoid Receptor
温馨提示：不可用于临床ZL。
