Dolutegravir-d3 RR Isomer，C20H16D3F2N3O5

分子式：C20H16D3F2N3O5；分子量：422.4；别名：(4R,​12aR)​-N-​[(2,​4-Difluorophenyl)​methyl]​-​3,​4,​6,​8,​12,​12a-​hexahydro-​7-​hydroxy-​4-​methyl-​6,​8-​dioxo-​2H-pPyrido[1',​2':4,​5]​pyrazino[2,​1-​b]​[1,​3]​oxazine-​9-​carboxamide-d3；应用：Isotope labelled Dolutegravir RR Isomer is an isomer of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.。