RUNX1/RUNX1T1 Dual Fusion FISH Probe Kit

These fluorescence in situ hybridization (FISH) probes are intended to detect the t(8;21)(q21.3;q22) reciprocal translocation involving the RUNX1 and RUNX1T1 gene regions.A translocation between chromosomes 8 and 21, t(8;21)(q21.3;q22), is seen in approximately 8% of adult patients and 12% of children with Acute Myeloid Leukemia (AML). Patients with t(8;21) alone have betterrisk status than patients with normal karyotype or with multiple molecular abnormalities. The RUNX1/RUNX1T1 Dual Color Dual Fusion Probes have been used in several studies to detect t(8;21). Know more at: http://www.creative-bioarray.com/RUNX1-RUNX1T1-Dual-Fusion-FISH-Probe-Kit-FHPC-093-item-4734.htm