分子式:C33H19D3ClF5N6O5;分子量:716.03;别名:4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-(2-fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)oxy)phenyl)picolinamide;应用:Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methyl-d3-picolinamide is the labeled analogue of Regorafenib N-Demethyl-N-4-(3-fluoro-4-methylphenoxy)-N-methylpicolinamide (R143005), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.;类别:Amines, Aromatics, Heterocycles, Impurities, Isotope Labelled Compounds。
温馨提示:不可用于临床ZL。