分子式:C24H36N6O2;分子量:440.58;外观:Light Yellow Solid;溶解性:Chloroform (Slightly, Heated), Ethyl Acetate (Slightly, Heated), Methanol (Slightly, Heated);别名:trans-4-[[2-(Butylamino)-5-[5-(4-morpholinylmethyl)-2-pyridinyl]-4-pyrimidinyl]amino]cyclohexanol; UNC2250;熔点:207-210ºC;应用:(1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol inhibits steady-state phosphorylation of endogenous Mer and blocks ligand-stimulated activation of a chimeric EGFR-Mer protein. (1r,4r)-4-((2-(Butylamino)-5-(5-(morpholinomethyl)pyridin-2-yl)pyrimidin-4-yl)amino)cyclohexanol also decreases colony-forming potential in rhabdoid and NSCLC tumor cells.;类别:Amines, Aromatics, Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates
温馨提示:不可用于临床ZL。