磷酸化Cortactin (Tyr466)抗体_详细资料

产品信息

抗体名：磷酸化皮层肌动蛋白抗体抗体英文名： phospho-Cortactin (Tyr466) Antibody 靶点： phospho-Cortactin (Tyr466) 浓度： 1mg/ml 应用范围： WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500 宿主： Rabbit 适应物种： Hu 标记物：无标记（PLlabs可供应生物素、酶、荧光素标记的抗体）克隆性：多克隆保存条件：保存于-20℃ 形态：液态亚型： Rabbit Polyclonal IgG 免疫原： PhosphoPeptide derived from human Cortactin around the phosphorylation site of Tyr466(YAp-TEA). 规格： 0.1ml

phospho-Cortactin (Tyr466) Antibody

Cat#：PL0302274

Isotype:Rabbit Polyclonal IgG

Immunogen：PhosphoPeptide derived from human Cortactin around the phosphorylation site of Tyr466(YAp-TEA).

Purification: Immunogen affinity purified

Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

Background：
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Alternate Names：
Cortactin (phospho Tyr466); Cortactin (phospho Y466); p-Cortactin (phospho Y466); Amplaxin; CTTN; EMS 1; EMS1; Mammary tumor and squamous cell carcinoma associated; Oncogene EMS1; p80/85 src substrate; Src substrate cortactin; SRC8_HUMAN.

Specificity Reaction：Hu

Application Notes:WB: 1:100-500 E: 1:500-1000 IHC: 1:100-500 IF: 1:100-500

Storage ：
Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

This product for research use only, not for use in humans, therapeutic or diagnostic procedures.

PLlabs公司可供应相应抗体的生物素、辣根过氧化物酶、荧光素（FITC、PE、 CY3、 CY5、 CY7、 PE- CY3/5/7)标记抗体，欢迎大家咨询订购。

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