磷酸化c-Jun (Ser73)抗体

 

 phospho-c-Jun (Ser73) Antibody
 

Cat#：PL0302155
 

Isotype:Rabbit Polyclonal IgG
 

Immunogen：PhosphoPeptide derived from human c-Jun around the phosphorylation site of Ser73.  
 

Purification: Immunogen affinity purified

Storage Buffer: PBS, pH 7.4(1%BSA and 0.1% Sodium azide)

Background：

C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutation of Ser63/73 renders c-Jun nonresponsive to mitogenic and stress induced signaling pathways.

Specificity Reaction：Hu, Mo, Rat, Chi, Dog, Pig, Cow, Hor, Sheep,

 

 

Store at –20ºC for one year. Avoid repeated freeze-thaw cycles. At 4ºC for 2-3 weeks after reconstituted.

 

 

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