Blood group and Lewis antigens 血型和Lewis抗原

 

组织-血型抗原又称HBGs（A，B，H），相关抗原是存在于红血细胞和呼吸道粘膜上皮表面，以及泌尿生殖系统和消化道的复杂碳水化合物。它们也以游离糖的形式存在于生物液体，如唾液、肠内容物，人乳（HMO）和血液中。 
§  分泌型(Se): 个体口腔粘膜分泌积极而表达的ABH抗原。分泌型个体表达分泌腺-岩藻糖转移酶FUT2产生H抗原。
§  非分泌型 (Se0): 非分泌型个体缺乏分泌腺转移酶，产生较短小的Lewisa抗原(Lea)。
§  孟买型: 个体由于FUT1基因突变， 缺乏循环系统里血红细胞的岩藻糖型ABH抗原（稀有表型）。
 
进一步阅读
Marionneau et al. 2001. ABH and Histo-blood Group antigens. Biochimie, 83; 565−573.
Tan et al. Norovirus and its HBGA receptors: an answer to historical puzzle. Trends in microbiology, Vol.13 No.6 (2005)
上海甄准生物提供组织-血型抗原低聚葡聚糖，原装进口，咨询/订购热线：400-002-3832

产品编号	产品名称			产品描述
规格: 5 mg, 25 mg, 100 mg, 1 g, 5 g
H血型抗原(血型O型) 原装进口，咨询/订购热线：400-002-3832
EOT-GLY030		H血型抗原二糖 Blood group H antigen disaccharide				Fucα1-2Gal  C12H22O10 FW 326.29 [16741-18-7] [24656-24-4] [146076-26-8]
EOT-GLY031-1		H血型抗原三糖，1型 Blood group H antigen triaose type 1				Fucα1-2Galβ1-3GlcNAc  C20H35O15 FW 529.49
EOT-GLY031-2		H血型抗原三糖，2型 Blood group H antigen triaose type 2				Fucα1-2Galβ1-4GlcNAc  C20H35O15 FW 529.49
EOT-GLY031-3		H血型抗原三糖，5型 2‘-岩藻乳糖/2’FL Blood group H antigen triaose type 5 2’Fucosyllactose/ 2’FL				Fucα1-2Galβ1-4Glc  C18H32O15 FW 488.43 [41263-94-9]
		Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722
EOT-GLY032-1		H血型抗原四糖，1型 Blood group H antigen tetraose type 1		Fucα1-2Galβ1-3GlcNAcβ1-3Gal C26H45NO20 FW 691.62
GLY032-2		H血型抗原四糖，2型 Blood group H antigen tetraose type 2		Fucα1-2Galβ1-4GlcNAcβ1-3Gal C26H45NO20 FW 691.62
EOT-GLY127		H血型抗原四糖，4型/Globo H四糖 Blood group H antigen tetraose type 4/ Globo H tetraose		Fucα1-2Galβ1-3GalNAcβ1-3Gal C26H45NO20 FW 691.62
EOT-GLY033-1		H血型抗原五糖，1型 乳-N-岩藻五糖 I (LNFP I)  Blood group H antigen pentaose type 1 Lacto-N-fucopentaose I (LNFP I)		Fucα1-2Galβ1-3GlcNAcβ1-3Galβ1-4Glc  C32H55NO25 FW 853.76 [7578-25-8]
		Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722
EOT-GLY033-2		H血型抗原五糖，2型 乳-N-新岩藻五糖 I (LNFP I)  Blood group H antigen pentaose type 2 Lacto-N-neofucopentaose I (LnNFP I)		Fucα1-2Galβ1-4GlcNAcβ1-3Galβ1-4Glc  C32H55NO25 FW 853.76
A血型抗原 原装进口，咨询/订购热线：400-021-8158
EOT-GLY034			A血型抗原三糖 Blood group A antigen triose	GalNAcα1-3(Fucα1-2)Gal C20H35NO15 FW 529.49 [49777-13-1]
EOT-GLY035-1			A血型抗原四糖，1型 Blood group A antigen tetraose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAc C28H48N2O20 FW 732.68
EOT-GLY035-2			A血型抗原四糖，2型 Blood group A antigen tetraose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAc C28H48N2O20 FW 732.6
EOT-GLY035-3			A血型抗原四糖，5型 Blood group A antigen tetraose type 5	GalNAcα1-3(Fucα1-2)Galβ1-4Glc C26H45NO20 FW 691.62 [59957-92-5]
EOT-GLY035-4			A血型 Lewisb抗原五糖，1型 Blood group A Lewisb antigen pentaose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAc  C34H58N2O24 FW 878.82
EOT-GLY035-5			A血型 LewisY抗原五糖，2型 Blood group A LewisY antigen pentaose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4(Fucα1-3)GlcNAc  C34H58N2O24 FW 878.82
EOT-GLY036-1			A血型抗原五糖，1型 Blood group A antigen pentaose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Gal  C34H58N2O25 FW 894.82 [50624-46-9]
EOT-GLY036-2			A血型抗原五糖，2型 Blood group A antigen pentaose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Gal  C34H58N2O25 FW 894.82
EOT-GLY128			A血型抗原五糖，4型 Blood group A antigen pentaose type 4		GalNAcα1-3(Fucα1-2)Galβ1-3GalNAcβ1-3Gal  C34H58N2O25 FW 894.82
EOT-GLY037-1			A血型抗原六糖，1型 Blood group A antigen hexaose type 1	GalNAcα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Galβ1-4Glc C40H68N2O30 FW 1056.96
EOT-GLY037-2			A血型抗原六糖，2型 Blood group A antigen hexaose type 2	GalNAcα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Galβ1-4Glc C40H68N2O30 FW 1056.96
B血型抗原 原装进口，咨询/订购热线：400-002-3832
EOT-GLY038-1	B血型抗原四糖，1型 Blood group B antigen tetraose type 1			Galα1-3(Fucα1-2)Galβ1-3GlcNAc C26H45NO20 FW 691.62
EOT-GLY038-2	B血型抗原四糖，2型 Blood group B antigen tetraose type 2			Galα1-3(Fucα1-2)Galβ1-4GlcNAc C26H45NO20 FW 691.62
EOT-GLY038-3	B血型抗原四糖，5型 Blood group B antigen tetraose type 5			Galα1-3(Fucα1-2)Galβ1-4Glc C24H42O20 FW 650.57
EOT-GLY038-4	B血型Lewisb抗原五糖，1型 Blood group B Lewisb antigen pentaose type 1			Galα1-3(Fucα1-2)Galβ1-3(Fucα1-4)GlcNAc  C32H55NO24 FW 837.77
EOT-GLY038-5	B血型Lewisb抗原五糖，1型 Blood group B LewisY antigen pentaose type 2			Galα1-3(Fucα1-2)Galβ1-4(Fucα1-3)GlcNAc  C32H55NO24 FW 837.77
EOT-GLY039-1	B血型抗原五糖，1型 Blood group B antigen pentaose type 1			Galα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Gal C32H55NO25 FW 853.76
EOT-GLY039-2	B血型抗原五糖，2型 Blood group B antigen pentaose type 2			Galα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Gal C32H55NO25 FW 853.76
EOT-GLY129	B血型抗原五糖，4型 Blood group B antigen pentaose type 4			Galα1-3(Fucα1-2)Galβ1-3GalNAcβ1-3Gal  C32H55NO25 FW 853.76
EOT-GLY040-1	B血型抗原六糖，1型 Blood group B antigen hexaose type 1			Galα1-3(Fucα1-2)Galβ1-3GlcNAcβ1-3Galβ1-4Glc C38H65NO30 FW 1015.90
EOT-GLY040-2	B血型抗原六糖，2型 Blood group B antigen hexaose type 2			Galα1-3(Fucα1-2)Galβ1-4GlcNAcβ1-3Galβ1-4Glc  C38H65NO30 FW 1015.90
Lewis抗原 原装进口，咨询/订购热线：400-002-3832
EOT-GLY049	LewisX抗原三糖 (LeX) LewisX (LeX) triaose SSEA-1 / CD15			Galβ1-4(Fucα1-3)GlcNAc C20H35NO15 FW 529.49 [71208-06-5]
EOT-GLY050	LewisX抗原四糖 (LeX) LewisX (LeX) tetraose			Galβ1-4(Fucα1-3)GlcNAcβ1-3Gal C26H45NO20 FW 691.62
EOT-GLY051	LewisX (抗原六糖 (LeX) LewisX (LeX)hexaose Lacto-N-neodifucohexaose (LNnDFH)			Galβ1-4GlcNAc  C14H25NO11 FW 383.35 [32181-59-2]
	Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722  Product provided for the following study : “Structural basis for the interaction between human milk oligosaccharide and the bacterial lectin PA-IIL of Pseudomonas aeruginosa” Perret S et al., 2005. Biochem J. Jul 15;389.
EOT-GLY048	LewisY抗原四糖 (LeY) LewisY (LeY) tetraose			Fucα1-2Galβ1-4(Fucα1-3)GlcNAc C26H45NO19 FW 675.63  [82993-43-9]
EOT-GLY052	LewisY抗原五糖 (LeY) LewisY (LeY) pentaose			Fucα1-2Galβ1-4(Fucα1-3)GlcNAcβ1-3Gal  C32H55NO24 FW 837.77
EOT-GLY046	Lewisa抗原三糖 (Lea) Lewisa (Lea) triaose			Galβ1-3(Fucα1-4)GlcNAc C20H35NO15 FW 529.49 [56570-03-7]
EOT-GLY054	Lewisa抗原四糖 (Lea) Lewisa (Lea)tetraose			Galβ1-3(Fucα1-4)GlcNAcβ1-3Gal C26H45NO20 FW 837.77
EOT-GLY055	Lewisa抗原六糖 (Lea) Lewisa (Lea) hexaose Lacto-N-difucohexaose II (LNDFH II)			Galβ1-3(Fucα1-4)GlcNAcβ1-3Galβ1-4(Fucα1-3)Glc C38H65NO29 FW 999.90 [62258-12-2]
	Human Milk Oligosaccharide Kunz et al., 2000. Ann Rev Nutr. 20, 699-722
EOT-GLY045	Lewisb抗原四糖 (Leb) Lewisb (Leb) tetraose			Fucα1-2Galβ1-3(Fucα1-4)GlcNAc C26H45NO19 FW 675.63 [80081-06-7]
EOT-GLY056	Lewisb抗原五糖 (Leb) Lewisb (Leb) pentaose			Fucα1-2Galβ1-3(Fucα1-4)GlcNAcβ1-3Gal  C32H55NO24 FW 837.77
	Receptor of gastric pathogenic strain Becker DJ, Lowe JB. 2003. Glycobiology. Jul; 13(7): 41R- 53R
EOT-GLY047	唾液酸 LewisX抗原四糖 (SLeX) Sialyl LewisX (sLeX) tetraose			Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAc C31H51N2O23Na FW 842.72 [98603-84-0]
EOT-GLY053	唾液酸 LewisX抗原五糖 (SLeX) Sialyl LewisX (sLeX) pentaose			Neu5Acα2-3Galβ1-4(Fucα1-3)GlcNAcβ1-3Gal  C37H61N2O28Na FW 1004.86
	Ligand of selectin-dependent leukocyte adhesion Berg EL et al,. 1991. J Biol Chem. 266(23):14869-72 Tumor-associated-antigen (TACA) Magnani JL. 1991. Glycobiology. Sep;1(4):318-20
EOT-GLY044	唾液酸 Lewisa抗原四糖 (SLea) Sialyl Lewisa (sLea) tetraose			Neu5Acα2-3Galβ1-3(Fucα1-4)GlcNAc C31H51N2O23Na FW 842.73 [92448-22-1]

温馨提示：不可用于临床ZL。