抗体英文名:
CATSPER Rabbit Polyclonal Antibody
应用范围:
WB IHC IF
宿主:
Rabbit
适应物种:
Human, Mouse, Rat
克隆性:
单克隆
保存条件:
Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at -20℃ for 12 months
形态:
Liquid
亚型:
IgG
免疫原:
KLH conjugated synthetic peptide derived from human CATSPER
规格:
50ul/100ul
规格: |
50ul |
产品价格: |
¥1500.0 |
规格: |
100ul |
产品价格: |
¥2000.0 |
Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials; it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH.