Recombinant Human Papillomavirus 18

Synonyms .Papillomavirus, HPV, Papilloma Virus 

Introduction  Human papillomavirus family consist of over 200 types. Over than 30 to 40 types of HPV are transferred via sexual contact and infect the anogenital region initiating genital warts. Persistent infection with "high-risk" HPV types results in skin warts and leads to precancerous lesions and invasive cancer. HPV infection is considered as a source for all incidents of cervical cancer. E2, E6, and E7 proteins of HPV-16 and 18 are considered the main viral oncoproteins that take part in cervical cancer. The type-specific antigen epitopes of E2, E6, and E7 proteins of HPV-16 are fused together and expressed in E. coli for diagnostic purpose. 

Recombinant Human Papillomavirus 18Description  The Recombinant HPV-18 comprised from the E2, E6 & E7 epitopes is expessed in E. coli having a Mw of 33kDa. The protein is fused to a GST-Tag and purified by standard chromatography. 

Source  E.Coli 

Purification Method  The recombinant HPV-16 fusion protein was purified by GSH affinity chromatography technique. 

Recombinant Human Papillomavirus 18Physical Appearence  Sterile filtered clear liquid formulation. 

Formulation The protein is formulated with 1x PBS and 0.5mM EDTA. 

Stability  2 years when when kept frozen at -20C to -80C. 

Applications  Used for lateral follow product and ELISA assay. 

Purity Greater than 95% pure as determined by 10% PAGE (Coomassie staining). 

Recombinant Human Papillomavirus 18Usage  CHIs products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.